Date published: 2026-2-14

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NARS2 Activators

NARS2 activators encompass a range of chemicals that can directly or indirectly modulate the function of the asparaginyl-tRNA synthetase. Key among these activators are foundational molecules like ATP and aminoacyl-tRNA, which play direct roles in the enzymatic activity of NARS2. ATP provides the necessary energy for aminoacylation, while the specific amino acid, asparagine, ensures the precise function of NARS2.

Mg2+ and zinc ions are known to influence the function of several enzymes, including aminoacyl-tRNA synthetases, by facilitating the binding of substrates or stabilizing enzyme structures. Additionally, molecules like forskolin, which elevates cAMP levels, and DTT, which acts as a reducing agent, can indirectly impact protein synthesis and the activity of enzymes like NARS2. Metabolic intermediates like phosphoenolpyruvic acid and pyruvate are involved in energy processes and the broader metabolic network, possibly influencing the balance and function of protein synthesis machinery, including NARS2.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Adenosine 5′-Triphosphate, disodium salt

987-65-5sc-202040
sc-202040A
1 g
5 g
$39.00
$75.00
9
(1)

ATP provides the energy for the aminoacylation process, and higher levels can enhance NARS2 function.

Magnesium chloride

7786-30-3sc-255260C
sc-255260B
sc-255260
sc-255260A
10 g
25 g
100 g
500 g
$28.00
$35.00
$48.00
$125.00
2
(1)

Mg2+ is essential for aminoacylation, and its presence can aid NARS2 function.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc ions can modulate the activity of some aminoacyl-tRNA synthetases.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin can raise cAMP levels, possibly indirectly affecting protein synthesis and NARS2 activity.

Phosphoenolpyruvic acid, monopotassium salt

4265-07-0sc-208168
sc-208168A
sc-208168B
100 mg
250 mg
1 g
$78.00
$155.00
$302.00
1
(2)

Involved in cellular energy processes; might support tRNA synthetase activities, including NARS2.

Adenylosuccinic acid

19046-78-7sc-214511
sc-214511A
sc-214511B
25 mg
100 mg
500 mg
$240.00
$800.00
$4000.00
2
(0)

A related metabolite in nucleotide synthesis and can potentially influence NARS2.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

Important for cellular redox balance and can indirectly influence enzymes like NARS2.

L-Leucine

61-90-5sc-364173
sc-364173A
25 g
100 g
$21.00
$62.00
(0)

Another amino acid that, in high concentrations, might influence aminoacyl-tRNA synthetase balance.