NARS2 activators encompass a range of chemicals that can directly or indirectly modulate the function of the asparaginyl-tRNA synthetase. Key among these activators are foundational molecules like ATP and aminoacyl-tRNA, which play direct roles in the enzymatic activity of NARS2. ATP provides the necessary energy for aminoacylation, while the specific amino acid, asparagine, ensures the precise function of NARS2.
Mg2+ and zinc ions are known to influence the function of several enzymes, including aminoacyl-tRNA synthetases, by facilitating the binding of substrates or stabilizing enzyme structures. Additionally, molecules like forskolin, which elevates cAMP levels, and DTT, which acts as a reducing agent, can indirectly impact protein synthesis and the activity of enzymes like NARS2. Metabolic intermediates like phosphoenolpyruvic acid and pyruvate are involved in energy processes and the broader metabolic network, possibly influencing the balance and function of protein synthesis machinery, including NARS2.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
ATP provides the energy for the aminoacylation process, and higher levels can enhance NARS2 function. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $28.00 $35.00 $48.00 $125.00 | 2 | |
Mg2+ is essential for aminoacylation, and its presence can aid NARS2 function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions can modulate the activity of some aminoacyl-tRNA synthetases. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin can raise cAMP levels, possibly indirectly affecting protein synthesis and NARS2 activity. | ||||||
Phosphoenolpyruvic acid, monopotassium salt | 4265-07-0 | sc-208168 sc-208168A sc-208168B | 100 mg 250 mg 1 g | $78.00 $155.00 $302.00 | 1 | |
Involved in cellular energy processes; might support tRNA synthetase activities, including NARS2. | ||||||
Adenylosuccinic acid | 19046-78-7 | sc-214511 sc-214511A sc-214511B | 25 mg 100 mg 500 mg | $240.00 $800.00 $4000.00 | 2 | |
A related metabolite in nucleotide synthesis and can potentially influence NARS2. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
Important for cellular redox balance and can indirectly influence enzymes like NARS2. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $62.00 | ||
Another amino acid that, in high concentrations, might influence aminoacyl-tRNA synthetase balance. | ||||||