Date published: 2025-10-12

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Na+ CP type IIIβ Activators

Na+ CP type IIIβ" likely refers to a subtype of the Type III sodium-dependent phosphate cotransporters (NaPi-III), specifically the β isoform. These transporters are integral membrane proteins involved in the regulation of phosphate homeostasis in the body by mediating the cotransport of sodium (Na+) and phosphate (Pi) ions across cell membranes.The Type III sodium-dependent phosphate cotransporters are part of a larger family of solute carrier transporters (SLC), particularly the SLC34 family. They play a crucial role in phosphate balance, which is vital for various physiological processes including bone formation, energy metabolism, and cell signaling.

The Type III transporters are characterized by their ability to transport phosphate ions into cells in a sodium-dependent manner, meaning the transport of phosphate is coupled with the transport of sodium ions. This coupling is essential for the efficient uptake of phosphate, especially in environments where phosphate concentration is low.The β isoform (IIIβ) of these transporters has specific characteristics and tissue distribution. It may differ from other isoforms in aspects such as regulation, affinity for phosphate, and response to various physiological and hormonal influences. These differences allow for a finely tuned regulation of phosphate homeostasis in different tissues and under various physiological conditions.

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