Myoferlin Inhibitors
Myoferlin Inhibitors include compounds that indirectly modulate the function of Myoferlin by influencing cellular processes related to vesicle trafficking, membrane dynamics, and cytoskeletal organization. These inhibitors do not target Myoferlin directly but affect the cellular mechanisms and pathways in which Myoferlin operates. Compounds such as Brefeldin A, Monensin, Dynasore, Nocodazole, and Cytochalasin D target vesicle trafficking and cytoskeletal dynamics. Brefeldin A and Monensin disrupt the function of the Golgi apparatus, which is crucial for the vesicle trafficking processes where Myoferlin is involved. Dynasore, Nocodazole, and Cytochalasin D, by affecting dynamin, microtubules, and actin filaments respectively, can disrupt the normal function of Myoferlin in vesicle movement and membrane repair.
Other inhibitors, including ML-7, Blebbistatin, Latrunculin A, Jasplakinolide, Wiskostatin, Y-27632, and Phalloidin, affect various aspects of cytoskeletal dynamics and related cellular processes. For instance, ML-7 and Blebbistatin, targeting myosin light chain kinase and myosin II, can impact cellular processes where Myoferlin plays a role. Latrunculin A, Jasplakinolide, and Phalloidin, by modulating actin filament dynamics, can influence Myoferlin's function in actin remodeling.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts transport between the endoplasmic reticulum and Golgi, potentially affecting Myoferlin's role in vesicle trafficking. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Alters Golgi apparatus function, which can influence Myoferlin's role in vesicle trafficking. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Inhibits dynamin, a GTPase involved in vesicle scission, potentially impacting Myoferlin-related vesicle trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics, which can impact vesicle transport processes involving Myoferlin. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin polymerization, affecting cytoskeletal dynamics crucial for vesicle movement where Myoferlin is involved. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase, potentially affecting Myoferlin-related actin dynamics. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II, potentially affecting cellular processes regulated by Myoferlin. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Binds to actin monomers, inhibiting actin polymerization which Myoferlin regulates. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, possibly counteracting Myoferlin's function in actin remodeling. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits N-WASP, a regulator of actin polymerization, possibly impacting Myoferlin function. | ||||||