Date published: 2025-10-25

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MYH7B Inhibitors

Common MYH7B Inhibitors include, but are not limited to Cycloheximide CAS 66-81-9, Actinomycin D CAS 50-76-0, Pyrrolidinedithiocarbamic acid ammonium salt CAS 5108-96-3, SP600125 CAS 129-56-6 and MG-132 [Z-Leu- Leu-Leu-CHO] CAS 133407-82-6.

MYH7B, a member of the myosin superfamily, is a protein involved in the basic motor functions at the cellular level. Myosins, as a general group, are actin-dependent motor molecules that play crucial roles in muscle contraction, intracellular motility, and the maintenance of cell shape. The myosin proteins convert chemical energy stored in ATP into mechanical work by producing force and movement along actin filaments. Each myosin has a specific domain structure and function, and MYH7B is unique in its composition and role within the cells. Specifically, MYH7B is associated with a distinct subset of cellular processes and is found in particular cell types and tissues.

Inhibitors targeting MYH7B are chemical entities that are designed to interfere with or reduce the activity of the MYH7B protein. Given the importance of myosins in cellular processes, inhibiting MYH7B could have profound effects on certain cellular functions. MYH7B inhibitors might operate by various mechanisms, such as obstructing the ATP-binding site, stopping actin-binding, or disrupting the conformational changes required for myosin's motor activity. By studying MYH7B inhibitors, researchers can gain a deeper understanding of the specific roles and functions of MYH7B within the cell, elucidating its contributions to cellular motility, organization, and other processes. Moreover, these inhibitors can serve as valuable tools for investigating the broader myosin superfamily and the intricate network of proteins and pathways with which they interact. As the field continues to explore the vast landscape of cellular motor functions, MYH7B inhibitors will undoubtedly play a role in unveiling the mysteries of cellular dynamics.

SEE ALSO...

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide blocks protein synthesis, potentially reducing the levels of MYH7B in cells.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

This compound binds to DNA, preventing RNA polymerase from carrying out transcription, possibly inhibiting MYH7B mRNA production.

Pyrrolidinedithiocarbamic acid ammonium salt

5108-96-3sc-203224
sc-203224A
5 g
25 g
$32.00
$63.00
11
(1)

PDTC can inhibit the NF-κB pathway. Given that NF-κB might regulate muscle-related genes, PDTC could potentially affect MYH7B expression.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

As a JNK pathway inhibitor, SP600125 might modulate muscle gene expression, potentially affecting MYH7B.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

By preventing proteasomal degradation, MG132 might stabilize proteins that down-regulate MYH7B.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

By modulating various signaling pathways, quercetin might inhibit pathways responsible for MYH7B expression.

Tyrphostin B42

133550-30-8sc-3556
5 mg
$26.00
4
(1)

By inhibiting JAK-STAT signaling, Tyrphostin B42 might affect muscle gene regulation, potentially down-regulating MYH7B.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

This PI3K-Akt pathway inhibitor might modulate muscle gene expression, possibly leading to reduced MYH7B levels.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

As a p38 MAPK inhibitor, SB203580 might affect muscle gene regulation, potentially inhibiting MYH7B expression.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

As a PI3K inhibitor, wortmannin might modulate pathways regulating muscle genes, possibly leading to reduced MYH7B expression.