Date published: 2025-9-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

MVD Inhibitors

MVD Inhibitors primarily revolve around the manipulation of the mevalonate pathway, essential for the synthesis of several bioactive molecules in the cell. The majority of the chemicals, such as Lovastatin, Simvastatin, and Atorvastatin, are statins which are specifically designed to inhibit the enzyme HMG-CoA reductase, an early step enzyme in the mevalonate pathway. By inhibiting the early stages of the pathway, these chemicals can indirectly impact the function or importance of MVD. Moreover, another group of compounds, bisphosphonates, like Alendronate and Zoledronate, target farnesyl diphosphate synthase. This action again indirectly affects MVD because both enzymes function in the same pathway. Finally, compounds like GGTI-298 and FTI-277 target the prenylation of proteins, a process downstream of the mevalonate pathway. By influencing these downstream effects, they indirectly emphasize the importance of upstream enzymes like MVD.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

6-Fluoromevalonate

2822-77-7sc-280541
sc-280541A
5 mg
25 mg
$235.00
$810.00
(0)

6-Fluoromevalonate serves as a pivotal intermediate in the mevalonate pathway, exhibiting unique reactivity due to the presence of a fluorine atom. This substitution alters the compound's electronic properties, enhancing its interaction with key enzymes involved in isoprenoid biosynthesis. The compound's structural conformation allows for specific binding affinities, influencing reaction rates and metabolic regulation. Its role in modulating enzyme activity highlights its significance in metabolic pathways.

Lovastatin

75330-75-5sc-200850
sc-200850A
sc-200850B
5 mg
25 mg
100 mg
$28.00
$88.00
$332.00
12
(1)

Though it primarily inhibits HMG-CoA reductase, its downstream effect can influence MVD.

Simvastatin

79902-63-9sc-200829
sc-200829A
sc-200829B
sc-200829C
50 mg
250 mg
1 g
5 g
$30.00
$87.00
$132.00
$434.00
13
(1)

Another HMG-CoA reductase inhibitor, affecting the overall mevalonate pathway.

Atorvastatin

134523-00-5sc-337542A
sc-337542
50 mg
100 mg
$252.00
$495.00
9
(1)

HMG-CoA reductase inhibitor; can influence the subsequent steps in the pathway.

Pravastatin, Sodium Salt

81131-70-6sc-203218
sc-203218A
sc-203218B
25 mg
100 mg
1 g
$68.00
$159.00
$772.00
2
(1)

Another compound affecting HMG-CoA reductase, indirectly influencing MVD.

Rosuvastatin

287714-41-4sc-481834
10 mg
$142.00
8
(0)

By inhibiting the earlier steps, it can potentially impact the function of MVD.

Fluvastatin

93957-54-1sc-279169
50 mg
$250.00
(0)

Another statin affecting the mevalonate pathway upstream of MVD.

Alendronate acid

66376-36-1sc-337520
5 g
$135.00
2
(0)

While primarily affecting bone resorption, they also inhibit farnesyl diphosphate synthase, another enzyme in the mevalonate pathway, which can indirectly affect MVD.

Zoledronic acid monohydrate

165800-06-6sc-202859
sc-202859A
sc-202859B
25 mg
100 mg
1 g
$95.00
$289.00
$658.00
5
(1)

Inhibits farnesyl diphosphate synthase in the mevalonate pathway.

GGTI 298

1217457-86-7sc-361184
sc-361184A
1 mg
5 mg
$189.00
$822.00
2
(1)

Geranylgeranyl transferase inhibitor; by inhibiting a downstream target of the mevalonate pathway, it can indirectly influence the function of MVD.