Date published: 2026-4-24

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MTH1 Antibodies

Santa Cruz Biotechnology provides a broad selection of MTH1 monoclonal antibodies for research focused on understanding MTH1 protein functions. MTH1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MTH1, or MutT Homolog 1, plays a critical role in cellular defense against oxidative stress by hydrolyzing oxidized nucleotides, thereby preventing their incorporation into DNA. This function is essential for maintaining genomic stability and preventing mutations that can lead to cancer. Given its importance in cellular metabolism and tumorigenesis, MTH1 has emerged as a potential therapeutic target in cancer research. MTH1 monoclonal antibodies enable researchers to explore cellular mechanisms and pathways involved in oxidative stress response. Investigating MTH1's role in DNA repair and genome stability can provide valuable insights into cancer development and potential treatment strategies. Understanding MTH1's functions may also reveal new therapeutic approaches for various diseases related to oxidative stress. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of MTH1's role in health and disease.

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MTH1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MTH1 Antibody (H-1)

sc-271082mouse IgG1 κ38-197 (h)WB, IP, IF, ELISAm, r, h
4
(4)

MTH1 Antibody (A-11)

sc-373709mouse IgG3 κ87-117 (m)WB, IP, IF, ELISAm, r
1
(2)

MTH1 Antibody (E-2)

sc-374011mouse IgG2a κ87-117 (m)WB, IP, IF, ELISAm, r

new

(1)

MTH1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MTH1 CRISPR/Cas9 KO Plasmid (h)

sc-403105hGene KnockoutGFP0
(0)

MTH1 HDR Plasmid (h)

sc-403105-HDRhHomology Directed RepairPuromycin0
(0)

MTH1 CRISPR/Cas9 KO Plasmid (m2)

sc-421739-KO-2mGene KnockoutGFP0
(0)

MTH1 HDR Plasmid (m2)

sc-421739-HDR-2mHomology Directed RepairPuromycin0
(0)

MTH1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MTH1 siRNA (h)

sc-62647hGene SilencingN/A
2
(0)

MTH1 shRNA Plasmid (h)

sc-62647-SHhGene SilencingPuromycin
2
(0)

MTH1 shRNA (h) Lentiviral Particles

sc-62647-VhGene SilencingPuromycin
2
(0)

MTH1 siRNA (m)

sc-62648mGene SilencingN/A0
(0)

MTH1 shRNA Plasmid (m)

sc-62648-SHmGene SilencingPuromycin0
(0)

MTH1 shRNA (m) Lentiviral Particles

sc-62648-VmGene SilencingPuromycin0
(0)