Date published: 2025-10-15

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MTA1 Inhibitors

MTA1 inhibitors belong to a significant class of chemical compounds that play a crucial role in modulating cellular processes. These inhibitors specifically target the Metastasis-Associated Protein 1 (MTA1), a protein known for its involvement in various cellular functions. MTA1 is a key component of chromatin remodeling complexes and is implicated in gene expression regulation, DNA repair, and other nuclear activities. The development of MTA1 inhibitors marks a significant stride in the field of molecular pharmacology, enabling researchers to delve deeper into the intricate mechanisms governing cellular behavior. Chemically, MTA1 inhibitors are designed to interact with the active site or binding pockets of the MTA1 protein, thereby disrupting its normal function. These inhibitors can vary in their structural features, but they typically possess moieties that allow them to bind effectively to the target site, forming stable interactions that impede the protein's activity. Researchers utilize various strategies, including structure-based drug design and high-throughput screening, to identify and optimize these compounds for improved affinity and specificity towards MTA1. By inhibiting MTA1's role in chromatin remodeling complexes, these compounds indirectly impact gene transcription, DNA replication, and repair processes.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

MS-275 is a histone deacetylase (HDAC) inhibitor that has shown potential in inhibiting MTA1 expression. By modulating the acetylation status of histones, it can affect gene expression, including that of MTA1.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin is a natural compound found in turmeric with anti-inflammatory and potential anti-cancer properties. It has been suggested to inhibit MTA1 expression, possibly through its effects on various signaling pathways.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG is a polyphenol present in green tea that has been studied for its potential anti-cancer properties. It may inhibit MTA1 expression through multiple mechanisms, including epigenetic regulation.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol is a compound found in grapes and red wine that has been investigated for its potential health benefits, including anti-cancer effects. It might inhibit MTA1 and other factors related to cancer progression.

Salinomycin

53003-10-4sc-253530
sc-253530C
sc-253530A
sc-253530B
5 mg
10 mg
25 mg
100 mg
$159.00
$236.00
$398.00
$465.00
1
(1)

Salinomycin is an antibiotic with emerging anti-cancer properties. It has been studied for its ability to inhibit cancer stem cells and metastasis, which might involve downregulation of MTA1.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is a flavonoid found in various fruits and vegetables. It has been reported to possess anti-cancer effects and could potentially downregulate MTA1 expression.

Thioridazine

50-52-2sc-473180
50 mg
$500.00
(0)

Thioridazine is an antipsychotic drug that has shown promise in inhibiting MTA1 expression in certain cancer types. Its potential anti-cancer properties are being explored.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$79.00
$300.00
32
(2)

Parthenolide is a compound found in the feverfew plant and has been investigated for its anti-cancer effects. It might inhibit MTA1 and other factors involved in cancer progression.

Celastrol, Celastrus scandens

34157-83-0sc-202534
10 mg
$155.00
6
(1)

Celastrol is a compound from the thunder god vine (Tripterygium wilfordii) that exhibits anti-inflammatory and anti-cancer properties. It could potentially inhibit MTA1-mediated metastasis.

Honokiol

35354-74-6sc-202653
sc-202653A
10 mg
25 mg
$118.00
$178.00
4
(1)

Honokiol is a natural compound found in the bark of magnolia trees. It has been studied for its anti-cancer effects and might impact MTA1 expression to inhibit metastasis.