MRP-L48 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Oligomycin inhibits ATP synthase in mitochondria, leading to a reduction in ATP production, which is necessary for the function of mitochondrial ribosomal proteins like MRP-L48, as their activity is energy-dependent. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Antimycin A blocks the electron transport chain at complex III, resulting in decreased ATP generation, which in turn can decrease the activity of MRP-L48 due to lower energy availability. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Chloramphenicol binds to bacterial ribosomes and can similarly bind to mitochondrial ribosomes due to structural homology, potentially inhibiting MRP-L48's role in mitochondrial protein synthesis. | ||||||
Doxycycline-d6 | 564-25-0 unlabeled | sc-218274 | 1 mg | $16500.00 | ||
Doxycycline, a tetracycline antibiotic, inhibits mitochondrial protein synthesis by binding to the ribosome, which could indirectly decrease the functional activity of MRP-L48 by inhibiting its role in protein translation. | ||||||
Ethidium bromide | 1239-45-8 | sc-203735 sc-203735A sc-203735B sc-203735C | 1 g 5 g 25 g 100 g | $47.00 $147.00 $576.00 $2045.00 | 12 | |
Ethidium Bromide intercalates into mitochondrial DNA, hindering replication and transcription, which could lead to reduced synthesis of components essential for MRP-L48 function. | ||||||
3′-Azido-3′-deoxythymidine | 30516-87-1 | sc-203319 | 10 mg | $60.00 | 2 | |
Zidovudine inhibits mitochondrial DNA polymerase gamma, which could lead to decreased mitochondrial DNA replication and transcription, indirectly affecting MRP-L48 activity. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Rotenone inhibits mitochondrial complex I, leading to reduced electron transport and ATP synthesis, which can indirectly inhibit MRP-L48 due to decreased energy supply. | ||||||
Atrazine | 1912-24-9 | sc-210846 | 5 g | $165.00 | 1 | |
Atrazine inhibits photosynthesis in plants and can impair mitochondrial electron transport in animals, potentially reducing ATP availability for MRP-L48 activity. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin can inhibit complex I of the electron transport chain, which may result in lowered ATP levels and thus indirectly inhibit MRP-L48. | ||||||
Carboxine | 5234-68-4 | sc-234286 | 250 mg | $21.00 | 1 | |
Carboxin inhibits mitochondrial complex II, disrupting electron transport and ATP synthesis, which could lead to reduced MRP-L48 activity due to energy shortage. | ||||||