Date published: 2025-10-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

MRP-L38 Inhibitors

MRP-L38 is an integral component of the mitochondrial ribosome, placing it at the heart of the mitochondrial protein synthesis process. In the realm of chemicals that may indirectly modulate its function, the inhibitors largely target mitochondrial operations. For example, Rotenone, Thenoyltrifluoroacetone, Antimycin A, and Myxothiazol, each target distinct complexes within the electron transport chain. Disruptions here can cascade down to affect the overall health and efficiency of the mitochondria, which in turn can impact MRP-L38. Other compounds like Oligomycin A, CCCP, and Valinomycin wield their effects by altering ATP synthesis or mitochondrial membrane potential. Such changes can result in a drastic alteration of the intramitochondrial environment, which may influence MRP-L38's stability or function. Lastly, antibiotics like Tetracycline, Chloramphenicol, and Doxycycline, known primarily for targeting bacterial ribosomes, may also demonstrate effects on the mitochondrial ribosome due to its prokaryotic ancestry.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rotenone

83-79-4sc-203242
sc-203242A
1 g
5 g
$89.00
$254.00
41
(1)

An inhibitor of mitochondrial complex I, can impact the electron transport chain, potentially affecting MRPL38 indirectly.

Oligomycin

1404-19-9sc-203342
sc-203342C
10 mg
1 g
$146.00
$12250.00
18
(2)

Targets ATP synthase in mitochondria, potentially influencing MRPL38's function by altering mitochondrial ATP levels.

Antimycin A

1397-94-0sc-202467
sc-202467A
sc-202467B
sc-202467C
5 mg
10 mg
1 g
3 g
$54.00
$62.00
$1642.00
$4600.00
51
(1)

An inhibitor of complex III in the electron transport chain, which could indirectly influence MRPL38.

2-Thenoyltrifluoroacetone

326-91-0sc-251801
5 g
$36.00
1
(1)

Inhibits mitochondrial complex II, potentially affecting pathways related to MRPL38.

Myxothiazol

76706-55-3sc-507550
1 mg
$145.00
(0)

Inhibits complex III of the electron transport chain, which might have a knock-on effect on MRPL38.

Carbonyl Cyanide m-Chlorophenylhydrazone

555-60-2sc-202984A
sc-202984
sc-202984B
100 mg
250 mg
500 mg
$75.00
$150.00
$235.00
8
(1)

Uncoupler of oxidative phosphorylation, potentially impacting MRPL38 through alterations in mitochondrial membrane potential.

Valinomycin

2001-95-8sc-200991
25 mg
$163.00
3
(1)

A potassium ionophore that disrupts mitochondrial membrane potential, potentially affecting MRPL38's function.

Atovaquone

95233-18-4sc-217675
10 mg
$265.00
2
(0)

Targets mitochondrial electron transport, potentially influencing MRPL38 indirectly.

Tetracycline

60-54-8sc-205858
sc-205858A
sc-205858B
sc-205858C
sc-205858D
10 g
25 g
100 g
500 g
1 kg
$62.00
$92.00
$265.00
$409.00
$622.00
6
(1)

Known to target bacterial ribosomes; it's plausible that at high concentrations it might have some effect on mitoribosomes and MRPL38.

Chloramphenicol

56-75-7sc-3594
25 g
$53.00
10
(1)

Inhibits bacterial ribosomes, and at elevated levels might show affinity for mitoribosomes, potentially affecting MRPL38.