MRP-L34 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporine A binds to cyclophilins and inhibits calcineurin, which is a phosphatase involved in activating T-cells. MRP-L34 is involved in mitochondrial protein synthesis, and T-cell activation requires a robust supply of ATP from mitochondria. Inhibition of T-cell activation by Cyclosporine A could reduce the demand for mitochondrial protein synthesis, thus indirectly reducing MRP-L34 activity. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $175.00 $600.00 $1179.00 $5100.00 $9180.00 | 26 | |
Oligomycin binds to ATP synthase, specifically the OSCP subunit, inhibiting ATP production. Reduced ATP levels can lead to lower demand for mitochondrial protein synthesis, where MRP-L34 is involved, thereby indirectly inhibiting its function. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Antimycin A binds to and inhibits complex III of the mitochondrial electron transport chain, which leads to decreased ATP production. Since MRP-L34 is part of the mitochondrial protein synthesis machinery, lower ATP levels can indirectly inhibit its activity. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $42.00 $152.00 $385.00 $845.00 $88.00 | 8 | |
Azide inhibits complex IV of the electron transport chain by binding to the heme cofactor within cytochrome c oxidase. This inhibition disrupts ATP synthesis, subsequently reducing the functional demand on MRP-L34 for mitochondrial protein synthesis. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
Dinitrophenol acts as a protonophore, uncoupling oxidative phosphorylation, which leads to a decrease in ATP production. This decrease can indirectly inhibit MRP-L34 by reducing the need for mitochondrial protein synthesis. | ||||||
Atrazine | 1912-24-9 | sc-210846 | 5 g | $165.00 | 1 | |
Atrazine inhibits photosynthesis in plants and can disrupt the electron transport chain in mitochondria. Inhibition of the electron transport chain can reduce ATP production, indirectly lowering MRP-L34 activity due to decreased mitochondrial protein synthesis. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Rotenone is an inhibitor of mitochondrial complex I, leading to reduced electron transport and ATP synthesis. This could indirectly inhibit MRP-L34 by decreasing the need for its role in mitochondrial protein synthesis. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $160.00 $319.00 | 3 | |
Actinonin is a peptide deformylase inhibitor, affecting the N-terminal processing of nascent proteins. As MRP-L34 is involved in mitochondrial translation, actinonin's impact on protein maturation could indirectly affect MRP-L34's role in this process. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Chloramphenicol binds to bacterial ribosomes and may affect mitochondrial ribosomes due to their similar structure. This could inhibit mitochondrial protein synthesis, where MRP-L34 is involved, leading to its indirect inhibition. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $62.00 $92.00 $265.00 $409.00 $622.00 | 6 | |
Tetracycline binds to the 30S subunit of bacterial ribosomes and can also affect mitochondrial ribosomes, potentially inhibiting the function of MRP-L34 in mitochondrial protein synthesis. | ||||||