MND1 Activators
The class of chemicals listed as MND1 Activators includes various compounds that indirectly influence MND1 through their effects on DNA repair mechanisms, homologous recombination, and related signaling pathways. These compounds are not direct activators of MND1 but may impact its function by modulating the cellular environment and processes related to meiotic recombination.Poly (ADP-ribose) polymerase (PARP) inhibitors such as Olaparib, Rucaparib, Niraparib, Veliparib, and Talazoparib are known for their role in inhibiting DNA repair, particularly in cells deficient in homologous recombination repair mechanisms. By influencing DNA repair pathways, these inhibitors may indirectly affect the function of MND1, which is crucial in homologous pairing and recombination during meiosis.
Inhibitors targeting key proteins involved in the DNA damage response, such as ATR, ATM, CHK1, CHK2, and DNA-PK, can also indirectly impact MND1. These inhibitors alter the cellular response to DNA damage and the regulation of cell cycle checkpoints, which are important processes in meiotic recombination where MND1 is involved.Compounds like B02, which stabilize RAD51, can enhance homologous recombination, a pathway in which MND1 plays a significant role. Similarly, inhibitors of BRCA1/2, such as MLN4924, by affecting homologous recombination, could indirectly influence MND1 activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
ATR inhibitors, like VE-821, could influence MND1 function indirectly by modulating DNA damage response and repair pathways. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
ATM inhibitors, such as KU-55933, may affect MND1 activity indirectly by influencing DNA repair and cellular response to DNA damage. | ||||||
PF 477736 | 952021-60-2 | sc-362781 sc-362781A | 5 mg 25 mg | $115.00 $431.00 | ||
CHK1 inhibitors, like PF-477736, could indirectly impact MND1 by altering cell cycle checkpoints and DNA repair processes. | ||||||
RAD51 Inhibitor B02 | 1290541-46-6 | sc-507533 | 10 mg | $95.00 | ||
Compounds that stabilize RAD51, like B02, could affect MND1 function indirectly by enhancing homologous recombination. | ||||||
ATM/ATR Kinase Inhibitor Inhibitor | 905973-89-9 | sc-202964 | 5 mg | $106.00 | 8 | |
Inhibitors of BRCA1/2, such as MLN4924, may impact MND1 indirectly by influencing DNA repair pathways, including homologous recombination. | ||||||
NU 7441 | 503468-95-9 | sc-208107 | 5 mg | $357.00 | 10 | |
DNA-PK inhibitors, like NU7441, could indirectly influence MND1 by modulating DNA repair mechanisms, especially non-homologous end joining. | ||||||