Date published: 2025-10-11

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MMP-27 Activators

The MMP-27 activators, as delineated, predominantly influence the activity of MMP-27 through the modulation of various cellular pathways. Resveratrol, for instance, through the activation of the SIRT1 pathway, brings to light how cellular longevity effects or SIRT1-regulated processes can shape the function of MMP-27. PMA, on the other hand, targets the PKC pathway, offering a gateway into MMP-27 modulation its expression is intertwined with PKC-related signals. ATRA and Sulforaphane, affecting the retinoid signaling and NRF2 pathway respectively, underscore the delicate balance between cellular signaling and protein activity. Both hint at the intersections of MMP-27 with retinoid-responsive elements and oxidative stress responses. With the focus on histone modifications, Anacardic acid provides insight into the significance of chromatin states, and how MMP-27's activity might be interwoven with p300-mediated processes. Inflammation, a paramount process in many cellular contexts, offers a rich avenue for MMP-27 modulation. Sodium salicylate's inhibition of the NF-kB pathway provides a window into how MMP-27 could be affected in an inflammatory context. The Syk pathway, a significant cell signaling mechanism, can influence MMP-27, especially with the action of Piceatannol. Trolox and Berberine, affecting oxidative stress pathways and energy homeostasis respectively, present opportunities to modulate MMP-27's activity through these diverse processes. In the realm of kinase-mediated signaling, both Quercetin and Genistein offer pathways to influence MMP-27's function. Lastly, the multifaceted Curcumin, with its modulation of the Akt pathway, serves as a prime example of how diverse cellular processes can intersect and influence the activity of proteins like MMP-27.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol can activate the SIRT1 pathway. If MMP-27 is regulated by SIRT1-mediated processes or is influenced by the cellular longevity effects modulated by Resveratrol, its function can be influenced.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates the PKC pathway. If MMP-27 expression is modulated by PKC-mediated cellular signaling, then PMA can increase its activity by enhancing the PKC pathway.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

ATRA modulates retinoid signaling. If MMP-27 expression or activity is associated with retinoid-responsive elements, its activity can be influenced by ATRA.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Sulforaphane activates the NRF2 pathway, responsible for oxidative stress responses. If MMP-27 is linked to oxidative stress response, its activity can be modulated by Sulforaphane-induced NRF2 pathway activation.

Anacardic Acid

16611-84-0sc-202463
sc-202463A
5 mg
25 mg
$100.00
$200.00
13
(1)

Anacardic acid inhibits p300 histone acetyltransferase, affecting histone acetylation. If MMP-27 expression is responsive to chromatin states modulated by p300, its activity can be influenced by Anacardic acid.

Sodium Salicylate

54-21-7sc-3520
sc-3520A
sc-3520B
sc-3520C
1 g
25 g
500 g
1 kg
$10.00
$25.00
$80.00
$136.00
8
(1)

Sodium salicylate inhibits the NF-kB pathway. If MMP-27 is upregulated during NF-kB-mediated inflammatory responses, this compound can influence its activity by modulating the pathway.

Piceatannol

10083-24-6sc-200610
sc-200610A
sc-200610B
1 mg
5 mg
25 mg
$50.00
$70.00
$195.00
11
(2)

Piceatannol inhibits the Syk pathway. If MMP-27 is modulated by Syk-mediated cellular responses, its activity can be influenced by Piceatannol's action on the Syk pathway.

Trolox

53188-07-1sc-200810
sc-200810A
sc-200810B
sc-200810C
sc-200810D
500 mg
1 g
5 g
25 g
100 g
$37.00
$66.00
$230.00
$665.00
$1678.00
39
(1)

Trolox acts as an antioxidant, affecting oxidative stress pathways. If MMP-27 plays roles in oxidative stress responses, its activity can be influenced by changes in these pathways induced by Trolox.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine activates AMPK pathway, affecting energy homeostasis. If MMP-27 interacts with energy homeostasis processes, its activity can be modulated by Berberine.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is a flavonoid known to inhibit PI3K pathway. If MMP-27's expression or activity is influenced by the PI3K pathway, Quercetin can indirectly modulate its function.