Date published: 2025-10-22

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MMACHC Antibodies

Santa Cruz Biotechnology delivers a wide array of MMACHC monoclonal antibodies for research focused on understanding MMACHC protein function and roles. MMACHC monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The MMACHC protein is crucial for the metabolism of vitamin B12, playing a significant role in the conversion of cobalamin into its active forms. Deficiencies or mutations in the MMACHC gene can lead to serious metabolic disorders, such as methylmalonic acidemia and homocystinuria, highlighting the importance of studying MMACHC in both clinical and research settings. Understanding MMACHC function can provide insights into the underlying mechanisms of metabolic disorders and aid in the development of potential therapeutic strategies. MMACHC research has revealed important connections between vitamin B12 metabolism and various health conditions. Investigating MMACHC expression patterns and interactions continues to uncover new aspects of cellular metabolism. Current research directions include exploring MMACHC's role in different tissue types and its potential as a therapeutic target. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of MMACHC's role in human health and disease.

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MMACHC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MMACHC Antibody (B-5)

sc-518236mouse IgG1 κ100-119 (h)WB, IP, IF, ELISAh

new

(1)

MMACHC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMACHC CRISPR/Cas9 KO Plasmid (h)

sc-408212hGene KnockoutGFP0
(0)

MMACHC HDR Plasmid (h)

sc-408212-HDRhHomology Directed RepairPuromycin0
(0)

MMACHC Double Nickase Plasmid (h)

sc-408212-NIChGene KnockoutPuromycin0
(0)

MMACHC Double Nickase Plasmid (h2)

sc-408212-NIC-2hGene KnockoutPuromycin0
(0)

MMACHC CRISPR/Cas9 KO Plasmid (m)

sc-426376mGene KnockoutGFP0
(0)

MMACHC HDR Plasmid (m)

sc-426376-HDRmHomology Directed RepairPuromycin0
(0)

MMACHC Double Nickase Plasmid (m)

sc-426376-NICmGene KnockoutPuromycin0
(0)

MMACHC Double Nickase Plasmid (m2)

sc-426376-NIC-2mGene KnockoutPuromycin0
(0)

MMACHC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMACHC CRISPR Activation Plasmid (h)

sc-408212-ACThGene ActivationPuro, Blast, Hygro0
(0)

MMACHC CRISPR Activation Plasmid (h2)

sc-408212-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MMACHC Lentiviral Activation Particles (h)

sc-408212-LAChGene ActivationPuro, Blast, Hygro0
(0)

MMACHC Lentiviral Activation Particles (h2)

sc-408212-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MMACHC CRISPR Activation Plasmid (m)

sc-426376-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MMACHC CRISPR Activation Plasmid (m2)

sc-426376-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MMACHC Lentiviral Activation Particles (m)

sc-426376-LACmGene ActivationPuro, Blast, Hygro0
(0)

MMACHC Lentiviral Activation Particles (m2)

sc-426376-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MMACHC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMACHC siRNA (h)

sc-88005hGene SilencingN/A0
(0)

MMACHC shRNA Plasmid (h)

sc-88005-SHhGene SilencingPuromycin0
(0)

MMACHC shRNA (h) Lentiviral Particles

sc-88005-VhGene SilencingPuromycin0
(0)

MMACHC siRNA (m)

sc-149475mGene SilencingN/A0
(0)

MMACHC shRNA Plasmid (m)

sc-149475-SHmGene SilencingPuromycin0
(0)

MMACHC shRNA (m) Lentiviral Particles

sc-149475-VmGene SilencingPuromycin0
(0)