MLL4 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide | 1375465-09-0 | sc-499486 | 5 mg | $340.00 | ||
This is a small molecule inhibitor that targets multiple lysine methyltransferases, including KMT2B. It has been reported to disrupt the interaction between KMT2B and its coactivators, thereby inhibiting its methyltransferase activity. | ||||||
THZ1 | 1604810-83-4 | sc-507542 | 1 mg | $95.00 | ||
Although THZ1 is primarily known as a CDK7 inhibitor, it also inhibits MLLTHZ1 has shown promise in research studies that investigate several cancer types, including acute myeloid leukemia and breast cancer. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
UNC1999 is a selective inhibitor of the lysine methyltransferases KMT2A (MLL1) and KMT2B (MLL4). It has demonstrated potent inhibitory activity against these enzymes in research studies. | ||||||
A-366 | 1527503-11-2 | sc-507495 | 10 mg | $195.00 | ||
A-366 is a small molecule inhibitor that selectively targets KMT2B and KMT2D (MLL2). It has been reported to inhibit the methyltransferase activity of these enzymes and exhibit antiproliferative effects in cancer cell lines. | ||||||
Epz004777 | 1338466-77-5 | sc-507560 | 100 mg | $575.00 | ||
EPZ004777 is a potent and selective inhibitor of KMT2B. It binds to the catalytic SET domain of the enzyme and inhibits its methyltransferase activity. | ||||||
UNC 1215 | 1415800-43-9 | sc-475020 | 10 mg | $380.00 | ||
UNC 1215 is a small molecule inhibitor that has been developed to target MLL3 and MLL4, both of which belong to the same family of lysine methyltransferases. It has been used in research to explore the biological functions of MLL4. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
E7438 is an inhibitor that has been developed to target various histone methyltransferases, including MLLIt. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $92.00 $243.00 $306.00 | ||
GSK126 is a selective inhibitor of the lysine methyltransferase KMT2B. It binds to the catalytic SET domain of KMT2B and inhibits its methyltransferase activity. | ||||||
SP2509 | 1423715-09-6 | sc-492604 | 5 mg | $284.00 | ||
SP-2509 is a small molecule inhibitor that targets the histone methyltransferases MLL1 and MLLIt has been explored in research studies. | ||||||