MEK-7 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $28.00 $80.00 $412.00 $1860.00 $2962.00 | 5 | |
Selumetinib is a potent and selective inhibitor of MEK1/2, impeding the MAPK signaling pathway. By targeting MEK, it disrupts the downstream activation of ERK1/2, hindering the transmission of proliferative signals. | ||||||
Trametinib | 871700-17-3 | sc-364639 sc-364639A sc-364639B | 5 mg 10 mg 1 g | $112.00 $163.00 $928.00 | 19 | |
Trametinib, a highly selective MEK inhibitor, modulates the MAPK pathway by impeding MEK1/2-mediated phosphorylation of ERK1/2. This disruption curtails downstream signaling, attenuating cellular processes associated with proliferation. | ||||||
Cobimetinib | 934660-93-2 | sc-507421 | 5 mg | $270.00 | ||
Cobimetinib acts as a potent MEK inhibitor, specifically targeting MEK1 and MEK2. By impeding MEK-mediated activation of ERK1/2, it disrupts the MAPK pathway, thereby hindering cellular processes linked to proliferation. | ||||||
BAY 869766 | 923032-37-5 | sc-364427 sc-364427A | 5 mg 10 mg | $240.00 $420.00 | 1 | |
BAY 869766, a selective MEK inhibitor, disrupts the MAPK pathway by targeting MEK1 and MEK2. By inhibiting MEK-mediated phosphorylation of ERK1/2, it hampers downstream signaling events essential for cell survival and proliferation. | ||||||
AS703026 | 1236699-92-5 | sc-364412 sc-364412A | 5 mg 10 mg | $80.00 $130.00 | ||
AS703026 (Pimasertib) functions as a MEK inhibitor, specifically targeting MEK1 and MEK2. By inhibiting MEK-mediated phosphorylation of ERK1/2, it disrupts the MAPK pathway, hindering downstream signaling events crucial for cell proliferation. | ||||||
MEK 162 | 606143-89-9 | sc-488879 | 10 mg | $306.00 | ||
MEK162, a potent MEK inhibitor, disrupts the MAPK pathway by specifically targeting MEK1 and MEK2. By inhibiting MEK-mediated phosphorylation of ERK1/2, it hampers downstream signaling events essential for cell survival and proliferation. | ||||||
TAK-733 | 1035555-63-5 | sc-364630 sc-364630A | 5 mg 10 mg | $340.00 $640.00 | 1 | |
TAK-733 acts as a MEK inhibitor, specifically targeting MEK1 and MEK2. By inhibiting MEK-mediated phosphorylation of ERK1/2, it disrupts the MAPK pathway, hindering downstream signaling events crucial for cell proliferation. | ||||||
AZD8330 | 869357-68-6 | sc-364425 sc-364425A | 5 mg 10 mg | $255.00 $450.00 | ||
AZD8330 serves as a MEK inhibitor, acting specifically on MEK1 and MEK2. By impeding MEK-mediated phosphorylation of ERK1/2, it disrupts the MAPK pathway, thereby hindering cellular processes associated with proliferation. | ||||||