MBLAC2 Inhibitors
The spectrum of MBLAC2 inhibitors, encompassing Batimastat, GW280264X, Marimastat, TAPI-2, Prinomastat, BB-94, AG-3340, ONO-4817, Ro 28-2653, CGS 27023A, Ilomastat, and UK 356618, constitutes a sophisticated arsenal with a unified purpose-directly targeting the enzyme through matrix metalloproteinase (MMP) inhibition. These compounds serve as precision tools, disrupting the intricate choreography of extracellular matrix (ECM) remodeling pathways, thereby orchestrating a nuanced modulation of MBLAC2 expression and function. At the core of this pharmacological intervention is the strategic blockade of MMPs, key players in the ECM dynamics. Batimastat, for instance, acts as a robust MMP inhibitor, impeding the enzymatic activity responsible for ECM cleavage. This disruption sets off a cascade of effects, including the modulation of MBLAC2. Similarly, GW280264X, Marimastat, TAPI-2, Prinomastat, BB-94, AG-3340, ONO-4817, Ro 28-2653, CGS 27023A, Ilomastat, and UK 356618 engage in a synchronized dance of MMP inhibition, intricately sculpting the ECM landscape to influence MBLAC2 in a targeted manner.
The intimate connection between ECM dynamics and MBLAC2 highlights a complex regulatory axis governing cellular processes. Disrupting ECM remodeling pathways not only directly impacts MBLAC2 but also reveals the interconnectedness of cellular responses orchestrated by this enzyme. This multifaceted approach provides researchers with a toolkit to dissect the intricate web of regulatory mechanisms within cellular processes modulated by MBLAC2. The pharmacological modulation of MBLAC2 by these inhibitors unveils a profound understanding of the enzyme's role in cellular homeostasis. The significance of extracellular matrix dynamics emerges as a central theme, underscoring the orchestrated interplay between MBLAC2 and the ECM. As researchers delve deeper into these interactions, the implications of manipulating MBLAC2 for various cellular functions become increasingly apparent. This comprehensive exploration not only advances our understanding of MBLAC2 regulation but also sets the stage for future investigations into the broader implications of targeting ECM dynamics in the context of cellular modulation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $179.00 $377.00 | 24 | |
Batimastat is a direct inhibitor of MBLAC2, functioning as a matrix metalloproteinase (MMP) inhibitor. By specifically targeting MMPs, Batimastat disrupts extracellular matrix remodeling pathways, indirectly influencing MBLAC2 activity. This inhibition prevents MMP-mediated cleavage events that might modulate MBLAC2 expression or function, highlighting the intricate interplay between matrix metalloproteinases and MBLAC2. | ||||||
GW 280264X | 866924-39-2 | sc-507540 | 5 mg | $720.00 | ||
GW280264X inhibits MBLAC2 directly by acting as a matrix metalloproteinase (MMP) inhibitor. Through targeted MMP inhibition, this compound disrupts extracellular matrix remodeling, influencing MBLAC2 indirectly. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
Marimastat acts as a direct inhibitor of MBLAC2 by targeting matrix metalloproteinases (MMPs). By inhibiting MMP activity, Marimastat disrupts extracellular matrix dynamics, indirectly influencing MBLAC2. This highlights the interconnected regulation between matrix metalloproteinases and MBLAC2, emphasizing the potential impact of extracellular matrix remodeling on MBLAC2 expression and function. | ||||||
TAPI-2 | 187034-31-7 | sc-205851 sc-205851A | 1 mg 5 mg | $286.00 $1019.00 | 15 | |
TAPI-2 serves as a direct inhibitor of MBLAC2 by inhibiting matrix metalloproteinases (MMPs). Through targeted MMP inhibition, TAPI-2 disrupts extracellular matrix remodeling pathways, indirectly modulating MBLAC2 activity. The specific inhibition of MMPs by TAPI-2 provides insights into the potential regulatory role of matrix metalloproteinases in influencing MBLAC2-mediated cellular processes. | ||||||
Prinomastat | 192329-42-3 | sc-507449 | 5 mg | $190.00 | ||
Prinomastat is a direct inhibitor of MBLAC2, functioning as a matrix metalloproteinase (MMP) inhibitor. By specifically targeting MMPs, Prinomastat disrupts extracellular matrix remodeling pathways, indirectly influencing MBLAC2 activity. This inhibition prevents MMP-mediated events that might modulate MBLAC2 expression or function, highlighting the intricate interplay between matrix metalloproteinases and MBLAC2. | ||||||
MMP Inhibitor V | 223472-31-9 | sc-203139 | 2 mg | $220.00 | 2 | |
ONO-4817 inhibits MBLAC2 directly by acting as a matrix metalloproteinase (MMP) inhibitor. Through targeted MMP inhibition, ONO-4817 disrupts extracellular matrix remodeling, influencing MBLAC2 indirectly. The modulation of MMP activity by ONO-4817 provides insights into the potential crosstalk between matrix metalloproteinases and MBLAC2, revealing a regulatory axis within cellular processes. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
Ilomastat is a direct inhibitor of MBLAC2, functioning as a matrix metalloproteinase (MMP) inhibitor. By specifically targeting MMPs, Ilomastat disrupts extracellular matrix remodeling pathways, indirectly influencing MBLAC2 activity. This inhibition prevents MMP-mediated cleavage events that might modulate MBLAC2 expression or function, highlighting the intricate interplay between matrix metalloproteinases and MBLAC2. | ||||||
UK 356618 | 230961-08-7 | sc-361392 sc-361392A | 5 mg 25 mg | $117.00 $444.00 | 2 | |
UK 356618 inhibits MBLAC2 directly by acting as a matrix metalloproteinase (MMP) inhibitor. Through targeted MMP inhibition, UK 356618 disrupts extracellular matrix remodeling, influencing MBLAC2 indirectly. The modulation of MMP activity by UK 356618 provides insights into the potential crosstalk between matrix metalloproteinases and MBLAC2, revealing a regulatory axis within cellular processes. | ||||||