Date published: 2026-1-22

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MAFbx Antibodies

Santa Cruz Biotechnology features a diverse variety of MAFbx Antibodies for research in muscle atrophy and related pathways. MAFbx Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MAFbx, also known as Atrogin-1, is an E3 ubiquitin ligase that plays a critical role in the ubiquitin-proteasome pathway, mediating protein degradation in muscle cells. Its regulation is essential for maintaining muscle mass and function, particularly during periods of stress or inactivity. Understanding MAFbx function in muscle atrophy can provide insights into various muscle-wasting diseases and potential therapeutic targets. Researchers can investigate protein expression patterns in different muscle tissues and cellular compartments. Advanced visualization techniques enable detailed examination of MAFbx localization and interactions with other proteins. Multiple detection methods allow for comprehensive analysis of MAFbx expression levels and activity. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of muscle biology and developing new therapeutic strategies for muscle-wasting conditions.

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MAFbx Antibodies

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MAFbx Antibody (F-9)

sc-166806mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
85
(12)

MAFbx CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAFbx CRISPR/Cas9 KO Plasmid (h)

sc-400908hGene KnockoutGFP0
(0)

MAFbx siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAFbx siRNA (h)

sc-43906hGene SilencingN/A0
(0)

MAFbx shRNA Plasmid (h)

sc-43906-SHhGene SilencingPuromycin0
(0)

MAFbx shRNA (h) Lentiviral Particles

sc-43906-VhGene SilencingPuromycin0
(0)

MAFbx siRNA (m)

sc-44807mGene SilencingN/A
1
(0)

MAFbx shRNA Plasmid (m)

sc-44807-SHmGene SilencingPuromycin
1
(0)

MAFbx shRNA (m) Lentiviral Particles

sc-44807-VmGene SilencingPuromycin
1
(0)

MAFbx siRNA (r)

sc-156172rGene SilencingN/A0
(0)

MAFbx Transfected Lysates

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MAFbx (m): 293T Lysate

sc-121485m
1
(0)