Date published: 2025-11-29

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MAD CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. MAD gene silencers are available as MAD CRISPR/Cas9 Knockout plasmids and MAD Double Nickase Plasmids. MAD CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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MAD CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAD1 CRISPR/Cas9 KO Plasmid (h)

sc-401885hGene KnockoutGFP0
(0)

MAD1 HDR Plasmid (h)

sc-401885-HDRhHomology Directed RepairPuromycin0
(0)

MAD1 Double Nickase Plasmid (h)

sc-401885-NIChGene KnockoutPuromycin0
(0)

MAD1 Double Nickase Plasmid (h2)

sc-401885-NIC-2hGene KnockoutPuromycin0
(0)

MAD1 CRISPR/Cas9 KO Plasmid (m)

sc-421520mGene KnockoutGFP0
(0)

MAD1 HDR Plasmid (m)

sc-421520-HDRmHomology Directed RepairPuromycin0
(0)

MAD1 Double Nickase Plasmid (m)

sc-421520-NICmGene KnockoutPuromycin0
(0)

MAD1 Double Nickase Plasmid (m2)

sc-421520-NIC-2mGene KnockoutPuromycin0
(0)

MAD2 CRISPR/Cas9 KO Plasmid (h)

sc-401027hGene KnockoutGFP0
(0)

MAD2 HDR Plasmid (h)

sc-401027-HDRhHomology Directed RepairPuromycin0
(0)

MAD2 Double Nickase Plasmid (h)

sc-401027-NIChGene KnockoutPuromycin0
(0)

MAD2 Double Nickase Plasmid (h2)

sc-401027-NIC-2hGene KnockoutPuromycin0
(0)

MAD2 CRISPR/Cas9 KO Plasmid (m)

sc-425010mGene KnockoutGFP0
(0)

MAD2 HDR Plasmid (m)

sc-425010-HDRmHomology Directed RepairPuromycin0
(0)

MAD2 Double Nickase Plasmid (m)

sc-425010-NICmGene KnockoutPuromycin0
(0)

MAD2 Double Nickase Plasmid (m2)

sc-425010-NIC-2mGene KnockoutPuromycin0
(0)

MAD2B CRISPR/Cas9 KO Plasmid (h)

sc-404007hGene KnockoutGFP0
(0)

MAD2B HDR Plasmid (h)

sc-404007-HDRhHomology Directed RepairPuromycin0
(0)

MAD2B Double Nickase Plasmid (h)

sc-404007-NIChGene KnockoutPuromycin0
(0)

MAD2B Double Nickase Plasmid (h2)

sc-404007-NIC-2hGene KnockoutPuromycin0
(0)

MAD2B CRISPR/Cas9 KO Plasmid (m)

sc-428124mGene KnockoutGFP0
(0)

MAD2B HDR Plasmid (m)

sc-428124-HDRmHomology Directed RepairPuromycin0
(0)

MAD2B Double Nickase Plasmid (m)

sc-428124-NICmGene KnockoutPuromycin0
(0)

MAD2B Double Nickase Plasmid (m2)

sc-428124-NIC-2mGene KnockoutPuromycin0
(0)

MAD CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAD1 CRISPR Activation Plasmid (h)

sc-401885-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAD1 CRISPR Activation Plasmid (h2)

sc-401885-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD1 Lentiviral Activation Particles (h)

sc-401885-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAD1 Lentiviral Activation Particles (h2)

sc-401885-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD1 CRISPR Activation Plasmid (m)

sc-421520-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAD1 CRISPR Activation Plasmid (m2)

sc-421520-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MAD1 Lentiviral Activation Particles (m)

sc-421520-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAD1 Lentiviral Activation Particles (m2)

sc-421520-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MAD2 CRISPR Activation Plasmid (h)

sc-401027-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAD2 CRISPR Activation Plasmid (h2)

sc-401027-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD2 Lentiviral Activation Particles (h)

sc-401027-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAD2 Lentiviral Activation Particles (h2)

sc-401027-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD2 CRISPR Activation Plasmid (m)

sc-425010-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAD2 CRISPR Activation Plasmid (m2)

sc-425010-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MAD2 Lentiviral Activation Particles (m)

sc-425010-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAD2 Lentiviral Activation Particles (m2)

sc-425010-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MAD2B CRISPR Activation Plasmid (h)

sc-404007-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAD2B CRISPR Activation Plasmid (h2)

sc-404007-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD2B Lentiviral Activation Particles (h)

sc-404007-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAD2B Lentiviral Activation Particles (h2)

sc-404007-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAD2B CRISPR Activation Plasmid (m)

sc-428124-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAD2B CRISPR Activation Plasmid (m2)

sc-428124-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MAD2B Lentiviral Activation Particles (m)

sc-428124-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAD2B Lentiviral Activation Particles (m2)

sc-428124-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)