MACF1 Activators

The chemical class of MACF1 Activators encompasses a diverse range of compounds that can indirectly influence the activity of MACF1 by modulating cytoskeletal dynamics and associated signaling pathways. These compounds do not directly activate MACF1 but can affect its function by altering the stability, organization, or dynamics of the actin and microtubule cytoskeletons, which are crucial for MACF1's role in cellular processes.

For instance, compounds like Paclitaxel and Nocodazole impact microtubule stability, which is significant as MACF1 functions to crosslink microtubules and actin filaments. Similarly, agents such as Jasplakinolide and Cytochalasin D, which influence actin filament dynamics, can indirectly modulate the activity of MACF1.