Ly-6D Activators
Ly-6D Activators encompass a diverse array of chemical compounds that indirectly promote the functional activity of Ly-6D through various signaling pathways. Forskolin and Isoproterenol both raise intracellular cAMP levels, leading to the activation of PKA, which may phosphorylate substrates involved in Ly-6D-associated pathways, particularly those enhancing its role in immune cell signaling. Sphingosine-1-phosphate, by acting on G protein-coupled receptors, could enhance the functionality of Ly-6D in lymphocyte trafficking and immune surveillance through downstream signaling effects.
Ionomycin, by increasing intracellular calcium, activates signaling pathways that could promote Ly-6D activity in immune communication. Furthermore, Adenosine and PGE2, through their actions on G protein-coupled receptors, may indirectly facilitate signaling cascades that enhance Ly-6D's role in modulating immune responses. The action of db-cAMP as a PKA activator suggests its potential in potentiating Ly-6D signaling in lymphocyte function, while Thapsigargin's disruption of calcium homeostasis could indirectly stimulate Ly-6D activity through calcium-dependent signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin acts by increasing intracellular cAMP levels, thus activating protein kinase A (PKA). PKA phosphorylation downstream can enhance Ly-6D signaling pathways, particularly those related to cell surface receptor signaling within immune cells. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which is involved in a multitude of cellular processes including regulation of signal transduction. Activation of PKC could enhance the signaling pathways that indirectly lead to an increase in Ly-6D functional activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, increases intracellular cAMP and thereby activates PKA. This activation can enhance Ly-6D-mediated signaling pathways associated with immune cell activation. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
This lipid signaling molecule engages G protein-coupled receptors affecting cell survival and migration, potentially enhancing Ly-6D activity in lymphocyte trafficking and immune surveillance through downstream signaling effects. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin, a calcium ionophore, raises intracellular calcium levels which can activate pathways that promote Ly-6D engagement in immune cell communication, thus enhancing its activity. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine modulates immune response via G protein-coupled receptor engagement, which can indirectly promote signaling pathways that enhance Ly-6D activity, especially in adaptive immune responses. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 acts through G protein-coupled receptors and can indirectly affect signaling cascades that enhance Ly-6D's functional activity in immune responses. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
The cAMP analog db-cAMP activates PKA, which can potentiate Ly-6D-related signaling in lymphocyte activation and function, thereby enhancing Ly-6D activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin disrupts calcium homeostasis, which may indirectly enhance Ly-6D function by stimulating calcium-dependent signaling pathways involved in immune cell signaling. | ||||||