LOC728393 Inhibitors
LOC728393 Inhibitors belongs to a group of compounds characterized by their ability to modulate the activity of the LOC728393 gene. LOC728393 is a non-coding RNA gene, and its inhibitors are designed to specifically target and inhibit the function of this gene. These inhibitors are often synthesized using advanced chemical techniques and can exhibit a high degree of specificity in their interactions with the LOC728393 gene. Researchers have focused on understanding the molecular mechanisms underlying the regulation of LOC728393 and the impact of its inhibition on various cellular processes.
Studies involving LOC728393 Inhibitors have sought to elucidate the role of LOC728393 in cellular functions and pathways. The inhibitors may function by binding to specific regions of the LOC728393 RNA, preventing its normal interactions with cellular components or other molecules. The exploration of LOC728393 Inhibitors has provided valuable insights into the intricate regulatory networks within cells. Additionally, researchers have investigated the potential implications of modulating LOC728393 activity in the context of various physiological and pathological conditions. Understanding the detailed mechanisms of action of these inhibitors is crucial for advancing our knowledge of gene regulation and may open avenues for further research in the broader field of molecular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
E-64 is an irreversible inhibitor that targets cysteine proteases. LOC728393, as a member of the ubiquitin-specific proteases, could be susceptible to the action of E-64 due to its potential interaction with the ubiquitin pathway, leading to inhibition of its deubiquitinating activity. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 is a potent, reversible, and cell-permeable proteasome inhibitor. It inhibits the degradation of ubiquitinated proteins. By stabilizing polyubiquitinated substrates, MG132 could indirectly impede the activity of LOC728393 by preventing substrate availability. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Lactacystin is a specific inhibitor of the proteasome. It inhibits the degradation of proteins involved in cell cycle regulation and apoptosis. By blocking proteasomal activity, lactacystin could indirectly reduce the functional activity of LOC728393 by altering the ubiquitin-protein conjugates it targets. | ||||||
PR 619 | 2645-32-1 | sc-476324 sc-476324A sc-476324B | 1 mg 5 mg 25 mg | $77.00 $188.00 $431.00 | 1 | |
PR-619 is a broad-spectrum deubiquitinase inhibitor. By inhibiting deubiquitinating enzymes, PR-619 could decrease the functional activity of LOC728393 by preventing the rescue of ubiquitin-tagged substrates, thus indirectly affecting its role in protein turnover. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
N-Ethylmaleimide is an organic compound that acts as an alkylating agent and inhibits cysteine proteases. By modifying the thiol groups in cysteine residues, it could inhibit the deubiquitinating activity of LOC728393 by disrupting its active site. | ||||||
WP1130 | 856243-80-6 | sc-364650 sc-364650A | 10 mg 50 mg | $490.00 $1484.00 | 1 | |
WP1130 is a selective deubiquitinase inhibitor. It inhibits the growth of cancer cells by increasing apoptotic rates. By inhibiting deubiquitinases, WP1130 could diminish the catalytic activity of LOC728393, which may be involved in the regulation of apoptosis through its deubiquitinating activities. | ||||||
IU1 | 314245-33-5 | sc-361215 sc-361215A sc-361215B | 10 mg 50 mg 100 mg | $138.00 $607.00 $866.00 | 2 | |
IU1 is a specific inhibitor of the deubiquitinating enzyme USP14. Although LOC728393 is a different deubiquitinating enzyme, the inhibition of USP14 could have an indirect effect on the activity of LOC728393 by modulating overall ubiquitin dynamics within the cell. | ||||||
NSC697923 | 343351-67-7 | sc-391107 sc-391107A | 1 mg 5 mg | $15.00 $52.00 | 3 | |
NSC697923 is a cell-permeable inhibitor that targets UBE2N and inhibits the formation of K63-linked polyubiquitin chains. By preventing polyubiquitin chain assembly, it could indirectly inhibit LOC728393 by reducing the substrate availability for its deubiquitinating activity. | ||||||
P22077 | 1247819-59-5 | sc-478536 | 10 mg | $165.00 | ||
P22077 is a potent inhibitor of USP7 and USP47. While LOC728393 is distinct in its specificity, the inhibition of these deubiquitinating enzymes could indirectly affect the function of LOC728393 by altering the cellular ubiquitin landscape. | ||||||