The chemical class termed LOC645359 Inhibitors is a category of compounds designed to selectively target the molecular entity known as LOC645359. The specific biological functions and cellular pathways associated with LOC645359 are currently under investigation, adding a layer of complexity to this chemical class. Inhibitors within this category are meticulously engineered molecules with the primary goal of modulating the activity or function of LOC645359, thereby exerting an inhibitory effect. Researchers engaged in the study of LOC645359 Inhibitors employ a comprehensive approach, integrating insights from structural biology, medicinal chemistry, and computational methods to unravel the intricate details of the molecular interactions between the inhibitors and the target LOC645359.
Structurally, LOC645359 Inhibitors are characterized by their unique molecular features, designed to facilitate selective binding to LOC645359. This selectivity is paramount to minimize off-target effects on other cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves an exhaustive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with LOC645359. As researchers delve deeper into the functional aspects of LOC645359 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of LOC645359 but also to advancing our broader understanding of cellular processes and molecular regulation. The exploration of LOC645359 Inhibitors represents a significant avenue for expanding fundamental knowledge in molecular pharmacology and cellular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
This antibiotic intercalates into DNA, preventing RNA polymerase from continuing transcription, which could nonspecifically reduce RGPD5 expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
As a diterpene triepoxide, triptolide has been shown to inhibit RNA polymerase II, which could reduce the transcription of a wide range of genes including RGPD5. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin targets RNA polymerase II and III, inhibiting mRNA synthesis which might lead to decreased expression of genes such as RGPD5. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
By terminating mRNA elongation, cordycepin could potentially reduce the levels of many mRNAs, possibly including that of RGPD5. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB selectively inhibits RNA polymerase II transcriptional elongation, which could result in reduced expression of genes, potentially including RGPD5. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
This compound inhibits eukaryotic protein synthesis, which could indirectly decrease RGPD5 levels by preventing its translation. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin causes premature termination during protein synthesis, which could nonspecifically decrease the synthesis of many proteins, including RGPD5. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a cyclin-dependent kinase inhibitor that can affect transcription regulation, potentially decreasing RGPD5 gene expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
By inhibiting BET bromodomains, JQ1 can alter chromatin accessibility and gene transcription, potentially affecting RGPD5 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an HDAC inhibitor, trichostatin A could lead to changes in chromatin structure and gene expression, possibly including RGPD5. | ||||||