IQANK1 is involved in calcium signaling pathways due to its IQ motif, this protein could play a role in a wide array of cellular activities, including muscle contraction, neurotransmitter release, cell growth, and gene expression. Its interaction with calmodulin could be calcium-dependent, allowing IQANK1 to act as a molecular switch that transduces calcium signals to effect cellular changes.
The presence of an ankyrin repeat suggests that IQANK1 may have a structural role, providing a scaffold for the assembly of multiprotein complexes at the cell membrane or within the cell. This could mean that IQANK1 is involved in organizing clusters of proteins necessary for signal transduction pathways or for maintaining cellular architecture. Given the nature of IQANK1, it's conceivable that this protein could be involved in neurological function, given that both calcium signaling and protein scaffolding are critical in neuronal communication and plasticity. Dysregulation of such a protein could potentially be linked to neurological disorders, where impaired calcium signaling and synaptic dysfunction are common features.
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