LOC100041471 Inhibitors
LOC100041471 contains inhibitors like compounds Imatinib, Dasatinib, and Bosutinib function as tyrosine kinase inhibitors, capable of interrupting signaling cascades vital for cellular proliferation and survival, which can affect the activity and expression of LOC100041471 if it is integrated within these pathways. Erlotinib and Lapatinib act by inhibiting EGFR and HER2/neu tyrosine kinases, respectively, with the potential to influence LOC100041471 activity if it relies on signals propagated by these receptors.
Inhibitors such as Sorafenib and Temsirolimus target the RAF/MEK/ERK and mTOR pathways, respectively, pathways that are central to cell growth and survival. Maraviroc, though not a kinase inhibitor, can affect chemokine signaling by blocking the CCR5 receptor, which can impact LOC100041471 if it is regulated by chemokine signaling. Zoledronic Acid, a bisphosphonate, can disrupt prenylation, a post-translational modification necessary for the localization and function of certain proteins; this can affect LOC100041471 if it requires prenylation for its activity. Gefitinib and Crizotinib are inhibitors of EGFR and ALK/ROS1 kinases, respectively, capable of altering signaling pathways that could influence LOC100041471 function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
A tyrosine kinase inhibitor that can suppress the BCR-ABL kinase, which can inhibit signaling pathways involved in cell proliferation and survival, affecting LOC100041471 if it is part of these pathways. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
An EGFR inhibitor that can prevent the activation of EGFR tyrosine kinase, which can inhibit downstream signaling affecting LOC100041471 if it relies on this pathway for its function. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A RAF kinase inhibitor that can block the RAF/MEK/ERK pathway, which can inhibit the activity of LOC100041471 if it interacts with this pathway. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A SRC family kinase inhibitor that can inhibit multiple tyrosine kinases, potentially affecting LOC100041471 if it is associated with any of these kinases. | ||||||
Lapatinib | 231277-92-2 | sc-353658 | 100 mg | $412.00 | 32 | |
A dual tyrosine kinase inhibitor that targets both EGFR and HER2/neu, which can inhibit signaling pathways linked to LOC100041471 if it is part of the HER2 pathway. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
A receptor tyrosine kinase inhibitor that can inhibit vascular endothelial growth factor receptors (VEGFRs), potentially affecting LOC100041471 if it is involved in angiogenesis signaling. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
A bisphosphonate that can inhibit farnesyl pyrophosphate synthase, potentially affecting LOC100041471 if it is prenylated for membrane attachment or signaling. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
An EGFR inhibitor that can block the kinase activity of EGFR, potentially affecting LOC100041471 if it relies on EGFR signaling for its activity. | ||||||