LOC100041314 Inhibitors
LOC100041314 inhibitors include compounds like Wortmannin and LY294002, which target the PI3K/Akt pathway, a key regulator of cell survival and metabolism. By inhibiting PI3K, these compounds can alter the phosphorylation state of downstream targets, which may include LOC100041314. U0126 and PD98059 are inhibitors of the MEK enzymes within the MAPK/ERK pathway, a critical pathway for cell proliferation and differentiation. By inhibiting MEK, these compounds could reduce the activation of ERK and potentially alter the activity of LOC100041314 if it is a downstream effector.
SB203580 and SP600125 are inhibitors of the p38 MAPK and JNK pathways, respectively, which are pathways activated by stress stimuli. By inhibiting these kinases, these compounds can reduce the cellular responses to stress, which may include the regulation of LOC100041314. Rapamycin specifically inhibits mTORC1, which is a central regulator of cell growth, and may influence LOC100041314 if it plays a role in these processes. NF-κB is a transcription factor involved in the inflammatory response, and its activity can be modulated by the IκB Kinase Inhibitor. If LOC100041314 is a gene regulated by NF-κB, this inhibitor could affect its expression. Cyclopamine and BML-275 target developmental pathways such as Hedgehog and BMP signaling, respectively.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor that can disrupt the PI3K/Akt signaling pathway, potentially affecting proteins regulated by this pathway, such as LOC100041314. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor that can affect inflammatory response pathways, potentially modulating the activity of proteins such as LOC100041314 involved in these pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, similar to Wortmannin, which can influence the PI3K/Akt pathway and therefore potentially affect LOC100041314 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor that can inhibit the mTORC1 complex, potentially impacting LOC100041314 if it is involved in cell growth and proliferation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that can block the JNK signaling pathway, potentially affecting proteins like LOC100041314 that may be regulated by stress responses. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1, which is involved in the MAPK/ERK pathway, potentially altering the function of downstream proteins such as LOC100041314. | ||||||
IKK 16 | 1186195-62-9 | sc-204009 sc-204009A | 10 mg 50 mg | $219.00 $924.00 | 2 | |
Inhibits NF-κB activation by preventing IκB degradation, potentially affecting LOC100041314 if it is regulated by NF-κB. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Hedgehog pathway inhibitor that can suppress the signaling involved in developmental processes, potentially impacting LOC100041314 if it is part of this pathway. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
Inhibits BMP signaling by targeting the BMP type I receptors ALK2, ALK3, and ALK6, potentially affecting proteins like LOC100041314 involved in this pathway. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can prevent the degradation of proteins, potentially stabilizing LOC100041314 if it is normally short-lived. | ||||||