The chemical class known as LOC100041179 Inhibitors comprises a series of compounds specifically engineered to target and inhibit the activity of the gene product of LOC100041179. This gene, identified through extensive genomic research, is implicated in a range of cellular processes and plays a significant role in cellular functions. The functionality of LOC100041179 is highly context-sensitive, with its role varying according to the cellular environment and external factors. The inhibitors developed for this gene are designed to selectively interact with the proteins or enzymes produced from the expression of LOC100041179. This selective interaction is crucial, as it directly affects the biochemical pathways that involve the LOC100041179 gene product. By inhibiting the activity of this gene product, these inhibitors aim to modify the associated cellular processes, potentially impacting specific cellular functions and mechanisms.
The development of LOC100041179 Inhibitors is a complex and interdisciplinary task that requires an integration of knowledge from molecular biology, chemistry, and bioinformatics. The initial phase of this development involves a comprehensive understanding of the structure and function of the LOC100041179 gene product. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are employed to gain a detailed insight into the target molecule. This foundational knowledge is essential for the rational design of inhibitors that are effective in their interaction with the target and exhibit a high degree of specificity. Typically, these inhibitors are small molecules, crafted for efficient penetration into cellular membranes and to establish a stable and potent interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interactions with the target molecule, often involving hydrogen bonds, hydrophobic interactions, and van der Waals forces. The effectiveness of these inhibitors is evaluated through various biochemical assays in vitro. These assays are critical in determining the inhibitors' potency, specificity, and overall behavior under controlled experimental conditions. Such research is vital for understanding the inhibitors' mechanism of action and for further exploration into their potential impact on the complex network of cellular pathways influenced by LOC100041179.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor that may lead to demethylation and potential upregulation of gene expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a histone deacetylase inhibitor that can modify chromatin structure to influence gene expression. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram can inhibit acetaldehyde dehydrogenase and has been shown to modulate various cellular pathways that could indirectly affect gene expression. | ||||||
1-β-D-Arabinofuranosylcytosine | 147-94-4 | sc-201628 sc-201628A sc-201628B sc-201628C sc-201628D | 1 g 5 g 25 g 100 g 250 g | $147.00 $258.00 $508.00 $717.00 $1432.00 | 1 | |
1-β-D-Arabinofuranosylcytosine is a nucleoside analog that can be incorporated into DNA, potentially leading to inhibition of DNA synthesis and affecting gene expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during translation, thus affecting protein synthesis which could lead to reduced gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits DNA topoisomerase I, leading to DNA damage and potential alterations in gene expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin, a nucleoside analog, can terminate RNA chain elongation, affecting transcription and subsequent gene expression. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C is a DNA crosslinking agent that can inhibit DNA replication and transcription, resulting in reduced gene expression. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate inhibits dihydrofolate reductase, leading to reduced nucleotide biosynthesis and potential downregulation of gene expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, which reduces the pool of nucleotides available for DNA synthesis, potentially affecting gene expression. | ||||||