Date published: 2025-12-18

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Liprin α1 Inhibitors

Liprin α1 inhibitors belong to a specific category of chemical compounds that have garnered attention in the field of molecular biology and synaptic function. Liprin α1, a member of the Liprin α family, is a multidomain scaffolding protein primarily found at the synapses of neurons. Synapses are specialized junctions that facilitate communication between neurons in the nervous system, allowing for the transmission of electrical and chemical signals. Liprin α1 plays a crucial role in organizing and regulating various synaptic processes, including synapse assembly, maturation, and plasticity. It serves as a scaffolding molecule, interacting with a multitude of synaptic proteins and influencing the structural and functional aspects of synapses. Liprin α1 inhibitors are chemical compounds designed to interact with Liprin α1, potentially modulating its functions and influencing synaptic organization and synaptic transmission.

The mechanism of action of Liprin α1 inhibitors typically involves their binding to specific regions or domains within the Liprin α1 protein. This interaction can lead to changes in Liprin α1's ability to interact with its synaptic binding partners, potentially affecting the assembly and stability of synaptic complexes and the regulation of synaptic processes. Consequently, Liprin α1 inhibitors may have implications for various synaptic functions, including synapse formation, maturation, and plasticity, offering insights into the molecular mechanisms that govern neuronal communication and synaptic organization. The study of Liprin α1 inhibitors is instrumental in advancing our understanding of synapse dynamics and function, providing valuable tools for investigating the roles of Liprin α1 in various neuronal contexts and its impact on the establishment and maintenance of synaptic connections.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

An anthracycline compound that intercalates DNA and inhibits topoisomerase II, potentially leading to reduced transcription including Liprin α1.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

A topoisomerase I inhibitor that induces DNA damage, possibly affecting transcription and thus Liprin α1 expression.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

A natural product that can inhibit translation initiation, potentially decreasing the synthesis of many proteins, including Liprin α1.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Known to inhibit lysosomal function and DNA replication, which might indirectly influence Liprin α1 expression levels.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$152.00
$515.00
(1)

An ionophore that disrupts Golgi function, possibly affecting protein trafficking and indirectly Liprin α1 expression.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

A compound that blocks N-linked glycosylation, which can impact protein folding and stability, possibly affecting Liprin α1.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

A GSK-3 inhibitor that can affect Wnt signaling and might influence Liprin α1 expression indirectly.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

A PKC activator that can modulate signaling pathways, potentially influencing transcription and Liprin α1 expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor, which may alter downstream signaling and potentially affect transcription of various genes including Liprin α1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor which can lead to altered protein synthesis and might indirectly result in decreased Liprin α1 levels.