Liprin α1 inhibitors belong to a specific category of chemical compounds that have garnered attention in the field of molecular biology and synaptic function. Liprin α1, a member of the Liprin α family, is a multidomain scaffolding protein primarily found at the synapses of neurons. Synapses are specialized junctions that facilitate communication between neurons in the nervous system, allowing for the transmission of electrical and chemical signals. Liprin α1 plays a crucial role in organizing and regulating various synaptic processes, including synapse assembly, maturation, and plasticity. It serves as a scaffolding molecule, interacting with a multitude of synaptic proteins and influencing the structural and functional aspects of synapses. Liprin α1 inhibitors are chemical compounds designed to interact with Liprin α1, potentially modulating its functions and influencing synaptic organization and synaptic transmission.
The mechanism of action of Liprin α1 inhibitors typically involves their binding to specific regions or domains within the Liprin α1 protein. This interaction can lead to changes in Liprin α1's ability to interact with its synaptic binding partners, potentially affecting the assembly and stability of synaptic complexes and the regulation of synaptic processes. Consequently, Liprin α1 inhibitors may have implications for various synaptic functions, including synapse formation, maturation, and plasticity, offering insights into the molecular mechanisms that govern neuronal communication and synaptic organization. The study of Liprin α1 inhibitors is instrumental in advancing our understanding of synapse dynamics and function, providing valuable tools for investigating the roles of Liprin α1 in various neuronal contexts and its impact on the establishment and maintenance of synaptic connections.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
An anthracycline compound that intercalates DNA and inhibits topoisomerase II, potentially leading to reduced transcription including Liprin α1. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
A topoisomerase I inhibitor that induces DNA damage, possibly affecting transcription and thus Liprin α1 expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
A natural product that can inhibit translation initiation, potentially decreasing the synthesis of many proteins, including Liprin α1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to inhibit lysosomal function and DNA replication, which might indirectly influence Liprin α1 expression levels. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
An ionophore that disrupts Golgi function, possibly affecting protein trafficking and indirectly Liprin α1 expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
A compound that blocks N-linked glycosylation, which can impact protein folding and stability, possibly affecting Liprin α1. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
A GSK-3 inhibitor that can affect Wnt signaling and might influence Liprin α1 expression indirectly. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
A PKC activator that can modulate signaling pathways, potentially influencing transcription and Liprin α1 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, which may alter downstream signaling and potentially affect transcription of various genes including Liprin α1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor which can lead to altered protein synthesis and might indirectly result in decreased Liprin α1 levels. | ||||||