LBA1 Inhibitors
LBA1 Inhibitors is a chemical class comprising a group of compounds specifically designed to interact with and modulate the activity of the LBA1 protein. LBA1, or Lipoxygenase Broad-specificity A1, is a protein with diverse cellular functions, and its precise role within various biological processes is an active subject of scientific investigation. These inhibitors are developed with a primary focus on targeting LBA1's functions while avoiding interference with other proteins or biological pathways. The primary goal behind the development of LBA1 inhibitors is to deepen our understanding of the complex cellular mechanisms in which LBA1 is involved and to explore potential avenues for further research and scientific exploration.
The process of developing LBA1 inhibitors involves a comprehensive approach to identify compounds that can selectively bind to LBA1 and thereby modulate its function. These inhibitors may exert their influence through various mechanisms, such as competitive binding, allosteric modulation, or interference with post-translational modifications. By perturbing LBA1's normal activity, researchers aim to unravel its role in different cellular processes and decipher its significance within various physiological contexts. LBA1 inhibitors may hold promise in shedding light on the fundamental biology of LBA1 and its potential implications in advancing our understanding of cellular function and regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, crucial for mRNA synthesis, which could reduce the expression of genes including UPF1. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase movement and thus transcription of genes like UPF1. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II by blocking the phosphorylation of its C-terminal domain, thereby reducing gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide inhibits transcription by affecting the activity of RNA polymerase I, II, and III, potentially reducing UPF1 expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin, an adenosine analog, can terminate mRNA chain elongation, which may decrease the expression of certain genes. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, which are essential for the transcription of genes, possibly influencing UPF1 expression. | ||||||
Oxamflatin | 151720-43-3 | sc-205960 sc-205960A | 1 mg 5 mg | $148.00 $461.00 | 4 | |
Oxamflatin is a histone deacetylase inhibitor, altering chromatin structure and potentially affecting gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin binds to RNA polymerase and inhibits transcription initiation, which could reduce expression of genes like UPF1. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits topoisomerase I, leading to DNA damage and potential downregulation of gene transcription. | ||||||
Mitoxantrone | 65271-80-9 | sc-207888 | 100 mg | $279.00 | 8 | |
Mitoxantrone intercalates into DNA and inhibits topoisomerase II, affecting transcription and potentially reducing UPF1 expression. | ||||||