Laminin β-2 Activators
Laminin β-2 activators encompass a variety of chemical compounds that enhance the functional activity of Laminin β-2 by influencing its interaction with cell surface receptors and modulating related signaling pathways. These activators function through diverse mechanisms, each uniquely contributing to the enhanced activity of Laminin β-2 in cellular processes. For example, compounds like Epigallocatechin gallate (EGCG) and Genistein work by modulating integrin signaling, which is crucial for Laminin β-2-mediated cell adhesion and signaling. These compounds enhance the interaction between Laminin β-2 and integrins, leading to more robust cell-matrix interactions and facilitating processes such as cell migration and differentiation.
Other activators, such as RGD Peptide and Heparin, influence the activity of Laminin β-2 by directly interacting with it or its receptors. RGD Peptide, by mimicking the cell-binding domain of extracellular matrix proteins, competitively modulates integrin-laminin interactions, thereby indirectly enhancing Laminin β-2-mediated cellular responses. Similarly, Heparin binds to Laminin β-2, stabilizing its interaction with cell surface receptors and enhancing its role in cell-matrix interactions. In addition to these, compounds like Ascorbic Acid and Zinc contribute indirectly by affecting the overall structural integrity of the extracellular matrix and modulating metalloproteinase activity, respectively. These actions facilitate a conducive environment for Laminin β-2's functional role in cell adhesion and migration.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a catechin found in green tea, enhances Laminin β-2 activity by modulating integrin signaling. Influencing integrin-ligand interactions, it indirectly enhances Laminin β-2-mediated cell adhesion and signaling, promoting cellular responses such as migration and differentiation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy-derived isoflavone, influences Laminin β-2 activity by modulating tyrosine kinase pathways, affecting integrin-mediated signaling. This indirectly enhances Laminin β-2's role in cell-matrix interactions and signaling pathways relevant to cellular differentiation and survival. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Ascorbic acid, or Vitamin C, plays a role in collagen synthesis and indirectly influences Laminin β-2 activity. By promoting collagen matrix formation, it enhances the structural integrity of the extracellular matrix, indirectly supporting Laminin β-2's role in cell-matrix interactions. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound in turmeric, indirectly enhances Laminin β-2 activity. It modulates various signaling pathways, including NF-κB and AP-1, linked to cell adhesion and migration processes where Laminin β-2 is involved. | ||||||
Heparin | 9005-49-6 | sc-507344 | 25 mg | $119.00 | 1 | |
Heparin, a glycosaminoglycan, binds to Laminin β-2, influencing its interaction with cell surface receptors. This binding enhances the stabilizing effect of Laminin β-2 on cell-matrix interactions, promoting cellular processes like adhesion and migration. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc, an essential mineral, influences Laminin β-2 activity by modulating metalloproteinase activity. This affects the extracellular matrix remodeling, indirectly enhancing Laminin β-2-mediated cell adhesion and migration. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P, a signaling lipid, enhances Laminin β-2 activity by influencing integrin-mediated signaling pathways. This modulation indirectly enhances Laminin β-2's role in cell adhesion and migration. | ||||||