KRTAP16-10 inhibitors belong to a class of chemical compounds designed to selectively target and interfere with the activity of KRTAP16-10, a protein from the Keratin-Associated Protein (KRTAP) family. KRTAPs are a diverse group of proteins that associate with keratins and are primarily expressed in hair and hair follicles. KRTAP16-10, as a member of this family, is presumed to play a role in the structural and mechanical properties of hair fibers.
The primary mechanism of action for KRTAP16-10 inhibitors typically involves their interaction with the KRTAP16-10 protein or its associated molecules, leading to the modulation of its normal function. By inhibiting KRTAP16-10, these compounds have the potential to influence processes related to hair development, structure, or other cellular functions in which this protein is involved. However, the exact roles and molecular pathways associated with KRTAP16-10 are still areas of active investigation. Scientists studying KRTAP16-10 inhibitors aim to uncover the precise functions and significance of KRTAP16-10 within the context of hair biology and other relevant cellular processes. These inhibitors serve as valuable tools for advancing our knowledge of KRTAP16-10 and its roles in cellular functions. In this context, they contribute to expanding our understanding of the intricate world of keratin-associated proteins and their impact on the biology of hair and related tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which is part of signaling pathways that can control protein translation and may affect KRTAP16-10 expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine is known to inhibit DNA and RNA synthesis by intercalating into DNA and RNA strands which may suppress KRTAP16-10 expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide inhibits translation initiation by binding to eIF4A, potentially reducing the expression of proteins such as KRTAP16-10. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit RNA polymerase II activity, which could downregulate KRTAP16-10 gene transcription. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane is known to modulate gene expression through epigenetic mechanisms, potentially affecting KRTAP16-10 expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during translation, leading to incomplete proteins and potentially reducing KRTAP16-10 levels. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin is a translation inhibitor which can inhibit peptide chain elongation, potentially reducing KRTAP16-10 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA at the transcription initiation complex, inhibiting RNA synthesis, potentially affecting KRTAP16-10 expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
Geldanamycin binds to Hsp90, affecting its function, which subsequently may destabilize client proteins and influence gene expression. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine inhibits protein synthesis by preventing the initial elongation step of translation, thus potentially decreasing protein levels. | ||||||