KLHL18 Activators
KLHL18 Activators chemical class would include agents that influence the protein ubiquitination process and cellular signaling pathways, modulating the function of KLHL18. These compounds, MG132 and Bortezomib, would work by decreasing the degradation of proteins, which could lead to an increase in the cellular substrates that KLHL18 interacts with. By stabilizing these proteins, the compounds may indirectly enhance the functional role of KLHL18 in protein ubiquitination and turnover.
PI3K, MAPK, JNK, and mTOR, including PIK-75, SB203580, LY294002, SP600125, and Rapamycin, can modulate signaling cascades that may influence the expression levels or activity of KLHL18. Additionally, natural compounds like curcumin and resveratrol, which interact with multiple cellular targets and pathways, could also indirectly impact the function of KLHL18. These KLHL18 Activators do not activate the protein directly but can lead to an upregulation of its activity or expression through their broad effects on cellular signaling networks.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PIK-75, hydrochloride | 372196-77-5 | sc-296089 sc-296089A | 1 mg 5 mg | $29.00 $124.00 | ||
PI3K inhibitor that might modulate pathways involving KLHL18. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAP kinase inhibitor, potentially influencing signaling pathways that KLHL18 is part of. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibitor of PI3K, might affect KLHL18 by altering downstream signaling pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that could modify cellular signaling processes involving KLHL18. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can affect protein synthesis, potentially influencing KLHL18's function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, might influence signaling pathways and processes that involve KLHL18. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound that might modulate various signaling pathways, potentially affecting KLHL18. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Might modulate protein activity and expression in pathways where KLHL18 is involved. | ||||||