Date published: 2026-1-9

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KLHDC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. KLHDC gene silencers are available as KLHDC CRISPR/Cas9 Knockout plasmids and KLHDC Double Nickase Plasmids. KLHDC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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KLHDC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLHDC1 CRISPR/Cas9 KO Plasmid (h)

sc-414191hGene KnockoutGFP0
(0)

KLHDC1 HDR Plasmid (h)

sc-414191-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC1 Double Nickase Plasmid (h)

sc-414191-NIChGene KnockoutPuromycin0
(0)

KLHDC1 Double Nickase Plasmid (h2)

sc-414191-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC1 CRISPR/Cas9 KO Plasmid (m)

sc-435434mGene KnockoutGFP0
(0)

KLHDC1 HDR Plasmid (m)

sc-435434-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC1 Double Nickase Plasmid (m)

sc-435434-NICmGene KnockoutPuromycin0
(0)

KLHDC1 Double Nickase Plasmid (m2)

sc-435434-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC2 CRISPR/Cas9 KO Plasmid (h)

sc-411772hGene KnockoutGFP0
(0)

KLHDC2 HDR Plasmid (h)

sc-411772-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC2 Double Nickase Plasmid (h)

sc-411772-NIChGene KnockoutPuromycin0
(0)

KLHDC2 Double Nickase Plasmid (h2)

sc-411772-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC2 CRISPR/Cas9 KO Plasmid (m)

sc-427450mGene KnockoutGFP0
(0)

KLHDC2 HDR Plasmid (m)

sc-427450-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC2 Double Nickase Plasmid (m)

sc-427450-NICmGene KnockoutPuromycin0
(0)

KLHDC2 Double Nickase Plasmid (m2)

sc-427450-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC3 CRISPR/Cas9 KO Plasmid (h)

sc-414085hGene KnockoutGFP0
(0)

KLHDC3 HDR Plasmid (h)

sc-414085-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC3 Double Nickase Plasmid (h)

sc-414085-NIChGene KnockoutPuromycin0
(0)

KLHDC3 Double Nickase Plasmid (h2)

sc-414085-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC3 CRISPR/Cas9 KO Plasmid (m)

sc-428048mGene KnockoutGFP0
(0)

KLHDC3 HDR Plasmid (m)

sc-428048-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC3 Double Nickase Plasmid (m)

sc-428048-NICmGene KnockoutPuromycin0
(0)

KLHDC3 Double Nickase Plasmid (m2)

sc-428048-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC4 CRISPR/Cas9 KO Plasmid (h)

sc-412327hGene KnockoutGFP0
(0)

KLHDC4 HDR Plasmid (h)

sc-412327-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC4 Double Nickase Plasmid (h)

sc-412327-NIChGene KnockoutPuromycin0
(0)

KLHDC4 Double Nickase Plasmid (h2)

sc-412327-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC4 CRISPR/Cas9 KO Plasmid (m)

sc-433399mGene KnockoutGFP0
(0)

KLHDC4 HDR Plasmid (m)

sc-433399-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC4 Double Nickase Plasmid (m)

sc-433399-NICmGene KnockoutPuromycin0
(0)

KLHDC4 Double Nickase Plasmid (m2)

sc-433399-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC5 CRISPR/Cas9 KO Plasmid (h)

sc-410067hGene KnockoutGFP0
(0)

KLHDC5 HDR Plasmid (h)

sc-410067-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC5 Double Nickase Plasmid (h)

sc-410067-NIChGene KnockoutPuromycin0
(0)

KLHDC5 Double Nickase Plasmid (h2)

sc-410067-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC7A CRISPR/Cas9 KO Plasmid (h)

sc-414308hGene KnockoutGFP0
(0)

KLHDC7A HDR Plasmid (h)

sc-414308-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC7A Double Nickase Plasmid (h)

sc-414308-NIChGene KnockoutPuromycin0
(0)

KLHDC7A Double Nickase Plasmid (h2)

sc-414308-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC7A CRISPR/Cas9 KO Plasmid (m)

sc-433934mGene KnockoutGFP0
(0)

KLHDC7A HDR Plasmid (m)

sc-433934-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC7A Double Nickase Plasmid (m)

sc-433934-NICmGene KnockoutPuromycin0
(0)

KLHDC7A Double Nickase Plasmid (m2)

sc-433934-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC7B CRISPR/Cas9 KO Plasmid (h)

sc-414026hGene KnockoutGFP0
(0)

KLHDC7B HDR Plasmid (h)

sc-414026-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC7B Double Nickase Plasmid (h)

sc-414026-NIChGene KnockoutPuromycin0
(0)

KLHDC7B Double Nickase Plasmid (h2)

sc-414026-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC7B CRISPR/Cas9 KO Plasmid (m)

sc-436838mGene KnockoutGFP0
(0)

KLHDC7B HDR Plasmid (m)

sc-436838-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC7B Double Nickase Plasmid (m)

sc-436838-NICmGene KnockoutPuromycin0
(0)

KLHDC7B Double Nickase Plasmid (m2)

sc-436838-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC8A CRISPR/Cas9 KO Plasmid (h)

sc-410001hGene KnockoutGFP0
(0)

KLHDC8A HDR Plasmid (h)

sc-410001-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC8A Double Nickase Plasmid (h)

sc-410001-NIChGene KnockoutPuromycin0
(0)

KLHDC8A Double Nickase Plasmid (h2)

sc-410001-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC8A CRISPR/Cas9 KO Plasmid (m)

sc-431867mGene KnockoutGFP0
(0)

KLHDC8A HDR Plasmid (m)

sc-431867-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC8A Double Nickase Plasmid (m)

sc-431867-NICmGene KnockoutPuromycin0
(0)

KLHDC8A Double Nickase Plasmid (m2)

sc-431867-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC8B CRISPR/Cas9 KO Plasmid (h)

sc-408555hGene KnockoutGFP0
(0)

KLHDC8B HDR Plasmid (h)

sc-408555-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC8B Double Nickase Plasmid (h)

sc-408555-NIChGene KnockoutPuromycin0
(0)

KLHDC8B Double Nickase Plasmid (h2)

sc-408555-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC8B CRISPR/Cas9 KO Plasmid (m)

sc-429639mGene KnockoutGFP0
(0)

KLHDC8B HDR Plasmid (m)

sc-429639-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC8B Double Nickase Plasmid (m)

sc-429639-NICmGene KnockoutPuromycin0
(0)

KLHDC8B Double Nickase Plasmid (m2)

sc-429639-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC9 CRISPR/Cas9 KO Plasmid (h)

sc-414287hGene KnockoutGFP0
(0)

KLHDC9 HDR Plasmid (h)

sc-414287-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC9 Double Nickase Plasmid (h)

sc-414287-NIChGene KnockoutPuromycin0
(0)

KLHDC9 Double Nickase Plasmid (h2)

sc-414287-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC9 CRISPR/Cas9 KO Plasmid (m)

sc-427210mGene KnockoutGFP0
(0)

KLHDC9 HDR Plasmid (m)

sc-427210-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC9 Double Nickase Plasmid (m)

sc-427210-NICmGene KnockoutPuromycin0
(0)

KLHDC9 Double Nickase Plasmid (m2)

sc-427210-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC10 CRISPR/Cas9 KO Plasmid (h)

sc-411649hGene KnockoutGFP0
(0)

KLHDC10 HDR Plasmid (h)

sc-411649-HDRhHomology Directed RepairPuromycin0
(0)

KLHDC10 Double Nickase Plasmid (h)

sc-411649-NIChGene KnockoutPuromycin0
(0)

KLHDC10 Double Nickase Plasmid (h2)

sc-411649-NIC-2hGene KnockoutPuromycin0
(0)

KLHDC10 CRISPR/Cas9 KO Plasmid (m)

sc-429419mGene KnockoutGFP0
(0)

KLHDC10 HDR Plasmid (m)

sc-429419-HDRmHomology Directed RepairPuromycin0
(0)

KLHDC10 Double Nickase Plasmid (m)

sc-429419-NICmGene KnockoutPuromycin0
(0)

KLHDC10 Double Nickase Plasmid (m2)

sc-429419-NIC-2mGene KnockoutPuromycin0
(0)

KLHDC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLHDC1 CRISPR Activation Plasmid (h)

sc-414191-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 CRISPR Activation Plasmid (h2)

sc-414191-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 Lentiviral Activation Particles (h)

sc-414191-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 Lentiviral Activation Particles (h2)

sc-414191-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 CRISPR Activation Plasmid (m)

sc-435434-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 CRISPR Activation Plasmid (m2)

sc-435434-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 Lentiviral Activation Particles (m)

sc-435434-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC1 Lentiviral Activation Particles (m2)

sc-435434-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 CRISPR Activation Plasmid (h)

sc-411772-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 CRISPR Activation Plasmid (h2)

sc-411772-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 Lentiviral Activation Particles (h)

sc-411772-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 Lentiviral Activation Particles (h2)

sc-411772-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 CRISPR Activation Plasmid (m)

sc-427450-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 CRISPR Activation Plasmid (m2)

sc-427450-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 Lentiviral Activation Particles (m)

sc-427450-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC2 Lentiviral Activation Particles (m2)

sc-427450-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 CRISPR Activation Plasmid (h)

sc-414085-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 CRISPR Activation Plasmid (h2)

sc-414085-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 Lentiviral Activation Particles (h)

sc-414085-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 Lentiviral Activation Particles (h2)

sc-414085-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 CRISPR Activation Plasmid (m)

sc-428048-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 CRISPR Activation Plasmid (m2)

sc-428048-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 Lentiviral Activation Particles (m)

sc-428048-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC3 Lentiviral Activation Particles (m2)

sc-428048-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 CRISPR Activation Plasmid (h)

sc-412327-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 CRISPR Activation Plasmid (h2)

sc-412327-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 Lentiviral Activation Particles (h)

sc-412327-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 Lentiviral Activation Particles (h2)

sc-412327-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 CRISPR Activation Plasmid (m)

sc-433399-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 CRISPR Activation Plasmid (m2)

sc-433399-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 Lentiviral Activation Particles (m)

sc-433399-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC4 Lentiviral Activation Particles (m2)

sc-433399-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC5 CRISPR Activation Plasmid (h)

sc-410067-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC5 CRISPR Activation Plasmid (h2)

sc-410067-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC5 Lentiviral Activation Particles (h)

sc-410067-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC5 Lentiviral Activation Particles (h2)

sc-410067-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A CRISPR Activation Plasmid (h)

sc-414308-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A CRISPR Activation Plasmid (h2)

sc-414308-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A Lentiviral Activation Particles (h)

sc-414308-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A Lentiviral Activation Particles (h2)

sc-414308-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A CRISPR Activation Plasmid (m)

sc-433934-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A CRISPR Activation Plasmid (m2)

sc-433934-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A Lentiviral Activation Particles (m)

sc-433934-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7A Lentiviral Activation Particles (m2)

sc-433934-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B CRISPR Activation Plasmid (h)

sc-414026-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B CRISPR Activation Plasmid (h2)

sc-414026-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B Lentiviral Activation Particles (h)

sc-414026-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B Lentiviral Activation Particles (h2)

sc-414026-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B CRISPR Activation Plasmid (m)

sc-436838-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B CRISPR Activation Plasmid (m2)

sc-436838-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B Lentiviral Activation Particles (m)

sc-436838-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC7B Lentiviral Activation Particles (m2)

sc-436838-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A CRISPR Activation Plasmid (h)

sc-410001-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A CRISPR Activation Plasmid (h2)

sc-410001-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A Lentiviral Activation Particles (h)

sc-410001-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A Lentiviral Activation Particles (h2)

sc-410001-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A CRISPR Activation Plasmid (m)

sc-431867-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A CRISPR Activation Plasmid (m2)

sc-431867-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A Lentiviral Activation Particles (m)

sc-431867-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8A Lentiviral Activation Particles (m2)

sc-431867-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B CRISPR Activation Plasmid (h)

sc-408555-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B CRISPR Activation Plasmid (h2)

sc-408555-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B Lentiviral Activation Particles (h)

sc-408555-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B Lentiviral Activation Particles (h2)

sc-408555-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B CRISPR Activation Plasmid (m)

sc-429639-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B CRISPR Activation Plasmid (m2)

sc-429639-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B Lentiviral Activation Particles (m)

sc-429639-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC8B Lentiviral Activation Particles (m2)

sc-429639-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 CRISPR Activation Plasmid (h)

sc-414287-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 CRISPR Activation Plasmid (h2)

sc-414287-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 Lentiviral Activation Particles (h)

sc-414287-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 Lentiviral Activation Particles (h2)

sc-414287-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 CRISPR Activation Plasmid (m)

sc-427210-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 CRISPR Activation Plasmid (m2)

sc-427210-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 Lentiviral Activation Particles (m)

sc-427210-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC9 Lentiviral Activation Particles (m2)

sc-427210-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 CRISPR Activation Plasmid (h)

sc-411649-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 CRISPR Activation Plasmid (h2)

sc-411649-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 Lentiviral Activation Particles (h)

sc-411649-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 Lentiviral Activation Particles (h2)

sc-411649-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 CRISPR Activation Plasmid (m)

sc-429419-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 CRISPR Activation Plasmid (m2)

sc-429419-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 Lentiviral Activation Particles (m)

sc-429419-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLHDC10 Lentiviral Activation Particles (m2)

sc-429419-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)