KLC1 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
S-Trityl-L-cysteine | 2799-07-7 | sc-202799 sc-202799A | 1 g 5 g | $32.00 $66.00 | 6 | |
S-Trityl-L-cysteine is a specific inhibitor of Kinesin Light Chain 1 (KLC1). By binding to KLC1, it disrupts the interaction between KLC1 and kinesin heavy chain, inhibiting the transport of cargoes along microtubules. This direct inhibition interferes with the cellular processes that rely on KLC1-mediated transport, suggesting a potential avenue for modulating intracellular trafficking and related functions. | ||||||
Apicidin | 183506-66-3 | sc-202061 sc-202061A | 1 mg 5 mg | $110.00 $343.00 | 9 | |
Apicidin is a histone deacetylase inhibitor that indirectly inhibits KLC1. By affecting the epigenetic regulation of gene expression, apicidin influences the expression of proteins involved in intracellular transport, including KLC1. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
AZD8055 is an mTOR inhibitor that indirectly inhibits KLC1. By suppressing the mTOR signaling pathway, AZD8055 interferes with the phosphorylation cascades that regulate KLC1 activity. This indirect modulation highlights the interconnected nature of mTOR signaling and KLC1-mediated processes, providing insights into potential therapeutic strategies to modulate intracellular transport. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Monastrol is a specific kinesin-5 inhibitor that indirectly affects KLC1 function. By perturbing mitotic spindle dynamics, monastrol alters the distribution of KLC1-associated cargoes during cell division. This indirect modulation provides insights into the role of KLC1 in mitosis and suggests potential avenues for disrupting KLC1-mediated processes during cell cycle progression. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
GSK690693 is an AKT inhibitor that indirectly inhibits KLC1. By suppressing the AKT signaling pathway, GSK690693 interferes with the phosphorylation cascades that regulate KLC1 activity. This indirect modulation highlights the interconnected nature of AKT signaling and KLC1-mediated processes, providing insights into potential therapeutic strategies to modulate intracellular transport. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Panobinostat is a histone deacetylase inhibitor that indirectly inhibits KLC1. By affecting the epigenetic regulation of gene expression, panobinostat influences the expression of proteins involved in intracellular transport, including KLC1. | ||||||
MLN 8054 | 869363-13-3 | sc-484828 | 5 mg | $398.00 | ||
MLN8054 is an Aurora A kinase inhibitor that indirectly inhibits KLC1. By disrupting the cell cycle progression and mitotic spindle assembly, MLN8054 indirectly influences the localization and activity of KLC1-associated cargoes. This modulation provides insights into the role of KLC1 in mitosis and suggests potential avenues for disrupting KLC1-mediated processes during cell division. | ||||||
BKM120 | 944396-07-0 | sc-364437 sc-364437A sc-364437B sc-364437C | 5 mg 10 mg 25 mg 50 mg | $176.00 $235.00 $281.00 $339.00 | 9 | |
BKM120 is a pan-class I PI3K inhibitor that indirectly inhibits KLC1. By suppressing the PI3K/AKT signaling pathway, BKM120 interferes with the phosphorylation cascades that regulate KLC1 activity. | ||||||
Tris Buffered Saline: 1 L of 1X | sc-362185 | 1 L | $21.00 | 3 | ||
Tubacin is a histone deacetylase 6 (HDAC6) inhibitor that indirectly inhibits KLC1. By modulating the acetylation status of microtubules and affecting the function of motor proteins, including kinesins, tubacin influences the dynamics of KLC1-mediated intracellular transport. | ||||||
AZD5363 | 1143532-39-1 | sc-503190 | 5 mg | $309.00 | ||
AZD5363 is an AKT inhibitor that indirectly inhibits KLC1. By suppressing the AKT signaling pathway, AZD5363 interferes with the phosphorylation cascades that regulate KLC1 activity. This indirect modulation highlights the interconnected nature of AKT signaling and KLC1-mediated processes, providing insights into potential therapeutic strategies to modulate intracellular transport. | ||||||