Date published: 2026-1-9

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KLC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. KLC gene silencers are available as KLC CRISPR/Cas9 Knockout plasmids and KLC Double Nickase Plasmids. KLC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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KLC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLC1 CRISPR/Cas9 KO Plasmid (h)

sc-401881hGene KnockoutGFP0
(0)

KLC1 HDR Plasmid (h)

sc-401881-HDRhHomology Directed RepairPuromycin0
(0)

KLC1 Double Nickase Plasmid (h)

sc-401881-NIChGene KnockoutPuromycin0
(0)

KLC1 Double Nickase Plasmid (h2)

sc-401881-NIC-2hGene KnockoutPuromycin0
(0)

KLC1 CRISPR/Cas9 KO Plasmid (m)

sc-421292mGene KnockoutGFP0
(0)

KLC1 HDR Plasmid (m)

sc-421292-HDRmHomology Directed RepairPuromycin0
(0)

KLC1 Double Nickase Plasmid (m)

sc-421292-NICmGene KnockoutPuromycin0
(0)

KLC1 Double Nickase Plasmid (m2)

sc-421292-NIC-2mGene KnockoutPuromycin0
(0)

KLC2 CRISPR/Cas9 KO Plasmid (h)

sc-406012hGene KnockoutGFP0
(0)

KLC2 HDR Plasmid (h)

sc-406012-HDRhHomology Directed RepairPuromycin0
(0)

KLC2 Double Nickase Plasmid (h)

sc-406012-NIChGene KnockoutPuromycin0
(0)

KLC2 Double Nickase Plasmid (h2)

sc-406012-NIC-2hGene KnockoutPuromycin0
(0)

KLC2 CRISPR/Cas9 KO Plasmid (m)

sc-421293mGene KnockoutGFP0
(0)

KLC2 HDR Plasmid (m)

sc-421293-HDRmHomology Directed RepairPuromycin0
(0)

KLC2 Double Nickase Plasmid (m)

sc-421293-NICmGene KnockoutPuromycin0
(0)

KLC2 Double Nickase Plasmid (m2)

sc-421293-NIC-2mGene KnockoutPuromycin0
(0)

KLC3 CRISPR/Cas9 KO Plasmid (h)

sc-409508hGene KnockoutGFP0
(0)

KLC3 HDR Plasmid (h)

sc-409508-HDRhHomology Directed RepairPuromycin0
(0)

KLC3 Double Nickase Plasmid (h)

sc-409508-NIChGene KnockoutPuromycin0
(0)

KLC3 Double Nickase Plasmid (h2)

sc-409508-NIC-2hGene KnockoutPuromycin0
(0)

KLC3 CRISPR/Cas9 KO Plasmid (m)

sc-433213mGene KnockoutGFP0
(0)

KLC3 HDR Plasmid (m)

sc-433213-HDRmHomology Directed RepairPuromycin0
(0)

KLC3 Double Nickase Plasmid (m)

sc-433213-NICmGene KnockoutPuromycin0
(0)

KLC3 Double Nickase Plasmid (m2)

sc-433213-NIC-2mGene KnockoutPuromycin0
(0)

KLC4 CRISPR/Cas9 KO Plasmid (h)

sc-408307hGene KnockoutGFP0
(0)

KLC4 HDR Plasmid (h)

sc-408307-HDRhHomology Directed RepairPuromycin0
(0)

KLC4 Double Nickase Plasmid (h)

sc-408307-NIChGene KnockoutPuromycin0
(0)

KLC4 Double Nickase Plasmid (h2)

sc-408307-NIC-2hGene KnockoutPuromycin0
(0)

KLC4 CRISPR/Cas9 KO Plasmid (m)

sc-428978mGene KnockoutGFP0
(0)

KLC4 HDR Plasmid (m)

sc-428978-HDRmHomology Directed RepairPuromycin0
(0)

KLC4 Double Nickase Plasmid (m)

sc-428978-NICmGene KnockoutPuromycin0
(0)

KLC4 Double Nickase Plasmid (m2)

sc-428978-NIC-2mGene KnockoutPuromycin0
(0)

KLC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLC1 CRISPR Activation Plasmid (h)

sc-401881-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (h2)

sc-401881-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (h)

sc-401881-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (h2)

sc-401881-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (m)

sc-421292-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (m2)

sc-421292-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (m)

sc-421292-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (m2)

sc-421292-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (h)

sc-406012-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (h2)

sc-406012-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (h)

sc-406012-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (h2)

sc-406012-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (m)

sc-421293-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (m2)

sc-421293-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (m)

sc-421293-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (m2)

sc-421293-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (h)

sc-409508-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (h2)

sc-409508-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (h)

sc-409508-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (h2)

sc-409508-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (m)

sc-433213-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (m2)

sc-433213-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (m)

sc-433213-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (m2)

sc-433213-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (h)

sc-408307-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (h2)

sc-408307-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (h)

sc-408307-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (h2)

sc-408307-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (m)

sc-428978-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (m2)

sc-428978-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (m)

sc-428978-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (m2)

sc-428978-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)