The class of chemicals listed as KIF24 Activators includes various compounds that indirectly influence KIF24 through their effects on microtubule dynamics, centrosome regulation, and related cellular processes. These compounds are not direct activators of KIF24 but may impact its function by modulating the cellular environment and mechanisms involved in microtubule dynamics and centrosome biology.Microtubule-targeting agents such as Paclitaxel, Nocodazole, Colchicine, Vincristine, Vinblastine, and Epothilone B play crucial roles in influencing microtubule dynamics, which are integral to the regulation of centrosomes and ciliogenesis, processes in which KIF24 is involved.
Inhibitors of pathways that influence centrosome biology, like Forskolin (increasing cAMP) and Lithium Chloride (inhibiting GSK-3), might indirectly impact KIF24 function by altering signaling dynamics relevant to centrosome regulation.Compounds like MG-132, a proteasome inhibitor, and Brefeldin A, which affects cellular trafficking, could also indirectly influence KIF24 by modulating the degradation and distribution of proteins involved in centrosome function.Roscovitine, a cyclin-dependent kinase inhibitor, may indirectly affect KIF24 by influencing cell cycle-related processes, which are closely linked to centrosome dynamics and ciliogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel, a microtubule stabilizer, may indirectly affect KIF24 by influencing microtubule dynamics and centrosome function. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B, a microtubule stabilizing agent, might influence KIF24 indirectly through its effects on microtubule dynamics. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin, known to increase cAMP levels, may indirectly affect KIF24 by modulating signaling pathways that influence centrosome biology. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride, a GSK-3 inhibitor, could impact KIF24 function indirectly by affecting pathways involved in microtubule and centrosome regulation. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG-132, a proteasome inhibitor, might indirectly influence KIF24 function by affecting protein degradation pathways related to centrosome components. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A, which disrupts Golgi apparatus function, could indirectly impact KIF24 function by influencing cellular trafficking and centrosome biology. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine, a cyclin-dependent kinase inhibitor, may affect KIF24 indirectly by modulating cell cycle-related processes and centrosome dynamics. | ||||||