KIAA0182 Inhibitors would be a theoretical group of chemical compounds designed to specifically target and inhibit the activity of the protein encoded by the gene formerly known as KIAA0182. In general, protein inhibitors work by binding to the protein of interest in such a way that the protein's natural function is impeded. This could involve blocking an active site, preventing conformational changes necessary for activity, or obstructing interactions with other molecules. In the case of KIAA0182, assuming it has enzymatic activity, inhibitors might resemble the substrate or product of its reaction, competitively inhibiting its activity.
The design and development of KIAA0182 Inhibitors would likely rely heavily on computational modeling and experimental biochemistry to determine the protein's structure and dynamics. Once the active or binding sites of KIAA0182 were identified, potential inhibitors could be screened using virtual docking techniques that predict how small molecules might interact with the protein. Lead compounds from these screens would then be synthesized and their inhibitory effects verified through in vitro assays. These assays might measure the binding affinity of the inhibitors, their specificity for KIAA0182 versus other proteins, and their impact on the protein's activity in a controlled environment. Assuming KIAA0182 plays a role in a particular cellular pathway, the inhibitors could be used to study the protein's function by observing the outcomes of its inhibition within cells or in a whole organism. Such studies could provide insights into how KIAA0182 interacts with other components of the cell and what roles it plays in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
It can modulate gene expression via retinoic acid receptors, potentially affecting a wide array of genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it may upregulate gene expression by altering chromatin structure. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound may demethylate DNA, potentially leading to the activation of silenced genes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By increasing cAMP, forskolin may activate PKA and subsequently CREB, which can induce gene transcription. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
It can bind to estrogen receptors and affect gene transcription in a wide variety of cells. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
This glucocorticoid can bind to glucocorticoid receptors, potentially affecting gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an HDAC inhibitor, it may enhance the transcription of numerous genes by changing chromatin accessibility. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Can induce ER stress, leading to the activation of the unfolded protein response and potentially altering gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
May modulate GSK-3 signaling, potentially affecting transcription factors and gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known to modulate various signaling pathways, which could lead to changes in gene expression profiles. | ||||||