Date published: 2025-10-25

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KIAA0182 Inhibitors

KIAA0182 Inhibitors would be a theoretical group of chemical compounds designed to specifically target and inhibit the activity of the protein encoded by the gene formerly known as KIAA0182. In general, protein inhibitors work by binding to the protein of interest in such a way that the protein's natural function is impeded. This could involve blocking an active site, preventing conformational changes necessary for activity, or obstructing interactions with other molecules. In the case of KIAA0182, assuming it has enzymatic activity, inhibitors might resemble the substrate or product of its reaction, competitively inhibiting its activity.

The design and development of KIAA0182 Inhibitors would likely rely heavily on computational modeling and experimental biochemistry to determine the protein's structure and dynamics. Once the active or binding sites of KIAA0182 were identified, potential inhibitors could be screened using virtual docking techniques that predict how small molecules might interact with the protein. Lead compounds from these screens would then be synthesized and their inhibitory effects verified through in vitro assays. These assays might measure the binding affinity of the inhibitors, their specificity for KIAA0182 versus other proteins, and their impact on the protein's activity in a controlled environment. Assuming KIAA0182 plays a role in a particular cellular pathway, the inhibitors could be used to study the protein's function by observing the outcomes of its inhibition within cells or in a whole organism. Such studies could provide insights into how KIAA0182 interacts with other components of the cell and what roles it plays in cellular processes.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

It can modulate gene expression via retinoic acid receptors, potentially affecting a wide array of genes.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As an HDAC inhibitor, it may upregulate gene expression by altering chromatin structure.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound may demethylate DNA, potentially leading to the activation of silenced genes.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

By increasing cAMP, forskolin may activate PKA and subsequently CREB, which can induce gene transcription.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

It can bind to estrogen receptors and affect gene transcription in a wide variety of cells.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

This glucocorticoid can bind to glucocorticoid receptors, potentially affecting gene expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

As an HDAC inhibitor, it may enhance the transcription of numerous genes by changing chromatin accessibility.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

Can induce ER stress, leading to the activation of the unfolded protein response and potentially altering gene expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

May modulate GSK-3 signaling, potentially affecting transcription factors and gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Known to modulate various signaling pathways, which could lead to changes in gene expression profiles.