Keratin 38 Activators
Keratin 38 activators are compounds that indirectly stimulate the expression of Keratin 38 by interacting with various cellular pathways and physiological processes. These activators are diverse, ranging from vitamins and trace elements to complex organic molecules, each contributing to the regulation of keratin expression through different mechanisms. Retinoic Acid and Vitamin D3, for example, are potent modulators of gene expression and have a specific role in the differentiation of keratinocytes, which directly correlates with the synthesis of keratins, including KRT38. Similarly, polyphenols such as Epigallocatechin gallate exert their effects through antioxidant properties and cellular differentiation pathways that are crucial for keratin regulation.
Amino acids like L-Cysteine and Methionine are fundamental for the structural integrity of keratins; they provide the necessary substrates for keratin fiber formation, thus influencing KRT38 expression. Minerals such as Zinc and Selenium serve as vital cofactors and antioxidants, respectively, supporting keratinocyte function and by extension, the synthesis of keratins. Copper peptide, a compound known for its role in skin regeneration, along with Sphinganine, a bioactive lipid, are involved in signaling cascades that have the potential to upregulate keratin production, highlighting the complexity and interconnectivity of pathways that regulate KRT38. Caffeine, a well-known stimulant, extends the anagen phase of hair growth, which may enhance KRT38 expression as part of the hair follicle's response to prolonged growth signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of Vitamin A that regulates gene expression through retinoic acid receptors; it can influence keratin gene expression, including KRT38, by modulating cellular differentiation processes in keratinocytes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea that has been shown to affect growth and differentiation in various cell types; it can upregulate keratin expression, potentially including KRT38, by influencing signaling pathways that govern cellular differentiation. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $69.00 $351.00 | ||
A vasodilator that can also affect hair growth; it may stimulate KRT38 expression as part of the complex signaling events leading to hair shaft production. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Its active form, calcitriol, acts via the vitamin D receptor to modulate gene expression; it can enhance the expression of keratins by affecting keratinocyte differentiation. | ||||||
L-Cysteine | 52-90-4 | sc-286072 sc-286072A sc-286072B sc-286072C sc-286072D | 25 g 100 g 500 g 5 kg 10 kg | $51.00 $112.00 $449.00 $1151.00 $2178.00 | 1 | |
An amino acid that is a building block of keratins; supplementation can support keratin synthesis, including KRT38, by providing the necessary substrate for the formation of disulfide bonds, which are crucial for keratin fiber structure. | ||||||
DL-Methionine | 59-51-8 | sc-397777 | 100 g | $45.00 | ||
Another sulfur-containing amino acid involved in the synthesis of keratins; providing this amino acid can support the production of keratins such as KRT38 by contributing to the structural components necessary for their assembly. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $41.00 $107.00 $333.00 | 1 | |
A vitamin that supports keratin infrastructure; it can promote KRT38 expression by enhancing the overall health and function of keratinocytes. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential mineral that acts as a cofactor for multiple enzymes; it can influence keratinocyte proliferation and differentiation, which may upregulate KRT38 expression. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
A lipid signaling molecule that can regulate keratinocyte growth and differentiation; may modulate KRT38 expression through the pathways that govern lipid metabolism and signal transduction in skin cells. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
An essential trace element with antioxidant properties; supports general cellular antioxidant systems, which can affect keratin expression including KRT38 by maintaining cellular health, thus promoting normal hair and skin physiology. | ||||||