Date published: 2025-10-25

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Keratin 2 Inhibitors

Keratin 2 inhibitors are a class of chemical compounds that specifically target and modulate the activity of keratin 2 proteins within the human body. Keratin 2 proteins are a subset of the keratin family, which are fibrous structural proteins found in various tissues, predominantly in the skin, hair, and nails. These proteins play a crucial role in maintaining the structural integrity and mechanical strength of these tissues. Keratin 2, in particular, is primarily expressed in the epidermis and is a key component of the skin's outermost layer, the stratum corneum. This layer acts as a barrier to protect the body from environmental factors such as pathogens, UV radiation, and dehydration. Therefore, the regulation of keratin 2 activity is vital for the overall health and function of the skin. Keratin 2 inhibitors are designed to interact with and modulate the function of keratin 2 proteins, typically by binding to specific sites on these proteins or by altering their expression levels. By doing so, these inhibitors can potentially influence the structural and mechanical properties of the skin, hair, and nails. Researchers and scientists are actively studying this class of compounds to better understand their effects on keratin 2 and explore their potential applications.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Urea

57-13-6sc-29114
sc-29114A
sc-29114B
1 kg
2 kg
5 kg
$30.00
$42.00
$76.00
17
(1)

Denatures proteins, including keratins, by disrupting hydrogen bonding.

Sodium dodecyl sulfate

151-21-3sc-264510
sc-264510A
sc-264510B
sc-264510C
25 g
100 g
500 g
1 kg
$50.00
$79.00
$280.00
$420.00
11
(1)

Acts as a detergent that can solubilize and denature keratin proteins in hair and nails.

Acetic acid

64-19-7sc-214462
sc-214462A
500 ml
2.5 L
$62.00
$104.00
5
(2)

Low pH can disrupt keratin structure and solubility.

FCM Fixation buffer (10X)

sc-3622
10 ml @ 10X
$61.00
16
(1)

Cross-links keratin proteins, which can inhibit their normal assembly and function.

β-Mercaptoethanol

60-24-2sc-202966A
sc-202966
100 ml
250 ml
$88.00
$118.00
10
(2)

Cleaves disulfide bonds in keratins, similarly to dithiothreitol.

Guanidine Hydrochloride

50-01-1sc-202637
sc-202637A
100 g
1 kg
$60.00
$195.00
1
(2)

Denatures and solubilizes proteins, including keratins, by chaotropic action.

2-Propanol

67-63-0sc-391000C
sc-391000
sc-391000B
sc-391000A
1 ml
25 ml
100 ml
500 ml
$32.00
$52.00
$62.00
$87.00
1
(0)

Precipitates proteins, including keratins, by dehydrating them and disrupting hydrophobic bonds.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Can disrupt protein structure, potentially affecting keratin assembly.

Lead(II) Acetate

301-04-2sc-507473
5 g
$83.00
(0)

Binds to thiol groups and could affect keratin structure by targeting cysteine residues.

Silver nitrate

7761-88-8sc-203378
sc-203378A
sc-203378B
25 g
100 g
500 g
$112.00
$371.00
$1060.00
1
(1)

Interacts with thiol groups and can lead to protein precipitation, impacting keratin.