Date published: 2026-2-25

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IRR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IRR Antibodies for studying insulin receptor-related proteins. IRR Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The insulin receptor (IR) plays a critical role in glucose homeostasis and cellular metabolism by mediating the effects of insulin. Dysregulation of the insulin receptor is associated with metabolic disorders, including type 2 diabetes and obesity, making it a significant target for therapeutic intervention. Understanding the function and signaling pathways of the insulin receptor is essential for developing strategies to combat these diseases. IRR monoclonal antibodies enable researchers to explore insulin receptor signaling cascades and their impact on metabolic regulation. Investigating insulin receptor pathways provides valuable information about cellular responses to insulin and glucose metabolism. Research utilizing IRR monoclonal antibodies helps identify potential therapeutic targets for metabolic disorders. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of insulin receptor biology and developing new treatments for metabolic diseases.

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IRR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IRR Antibody (I-63)

sc-100303mouse IgG1 κ651-760 (h)WB, IP, IF, IHC(P), ELISAh

new

(3)

IRRα Antibody (D-3)

sc-515888mouse IgG1619-715 (h)WB, IP, IF, ELISAm, r, h

new

(1)

IRR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRRα/β HDR Plasmid (m)

sc-423895-HDRmHomology Directed RepairPuromycin0
(0)

IRR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRRα/β siRNA (h)

sc-40081hGene SilencingN/A0
(0)

IRRα/β siRNA (m)

sc-40082mGene SilencingN/A
1
(0)

IRRβ shRNA Plasmid (h)

sc-40081-SHhGene SilencingPuromycin0
(0)

IRRβ shRNA (h) Lentiviral Particles

sc-40081-VhGene SilencingPuromycin0
(0)

IRRβ shRNA Plasmid (m)

sc-40082-SHmGene SilencingPuromycin
1
(0)

IRRβ shRNA (m) Lentiviral Particles

sc-40082-VmGene SilencingPuromycin
1
(0)