IQCF5, or IQ Motif Containing F5, is a relatively uncharacterized human protein. Its name refers to the presence of an IQ motif, which is a specific sequence of amino acids known to bind calcium ions and calmodulin, suggesting a potential role in calcium-mediated signaling pathways.The IQ motif is typically composed of 1 to 5 repeats of a consensus sequence and is found in a variety of proteins, including myosin regulatory light chains and other proteins involved in cellular signaling and cytoskeletal organization. The presence of this motif in IQCF5 implies that it may interact with calmodulin in a calcium-dependent manner, which could affect various cellular functions such as muscle contraction, cell motility, or intracellular signaling.
However, the exact biological function of IQCF5 remains elusive. It is not widely studied, and its expression patterns, cellular localization, and interacting partners are not well documented, leaving much to be discovered about its role in human physiology and disease.Given its name and the presence of the IQ motif, it is plausible that IQCF5 could be implicated in the regulation of contractile or motile systems within cells, potentially through modulation of calcium signaling. This would align with known functions of other proteins containing similar motifs.
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