Date published: 2025-10-19

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IL-27R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IL-27R monoclonal antibodies for investigating the IL-27 receptor in various biological processes. IL-27R monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The IL-27 receptor mediates the effects of IL-27, a cytokine involved in the regulation of immune responses and inflammation. IL-27R plays a significant role in the differentiation of T cells and the modulation of immune responses, making it an important target for studies related to autoimmune diseases and cancer. Research focused on IL-27R has revealed its importance in maintaining immune system balance and homeostasis. Understanding IL-27R function can provide insights into therapeutic strategies for various immune-related conditions. Ongoing studies continue to uncover new aspects of IL-27R signaling pathways and their implications in disease progression. Current research highlights the potential of IL-27R as a therapeutic target in treating inflammatory disorders. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of immune system regulation and disease mechanisms.

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IL-27R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-27Rα Antibody (F-7)

sc-376309mouse IgG1 κ91-340 (h)WB, IP, IF, ELISAh
3
(1)

IL-27Rα Antibody (J126)

sc-80078mouse IgG2b(h)WB, IPh
2
(1)

IL-27R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-27Rα CRISPR/Cas9 KO Plasmid (h)

sc-405846hGene KnockoutGFP0
(0)

IL-27Rα CRISPR/Cas9 KO Plasmid (h2)

sc-405846-KO-2hGene KnockoutGFP0
(0)

IL-27Rα HDR Plasmid (h2)

sc-405846-HDR-2hHomology Directed RepairPuromycin0
(0)

IL-27Rα Double Nickase Plasmid (h)

sc-405846-NIChGene KnockoutPuromycin0
(0)

IL-27Rα Double Nickase Plasmid (h2)

sc-405846-NIC-2hGene KnockoutPuromycin0
(0)

IL-27Rα CRISPR/Cas9 KO Plasmid (m)

sc-424540mGene KnockoutGFP0
(0)

IL-27Rα HDR Plasmid (m)

sc-424540-HDRmHomology Directed RepairPuromycin0
(0)

IL-27Rα Double Nickase Plasmid (m)

sc-424540-NICmGene KnockoutPuromycin0
(0)

IL-27Rα Double Nickase Plasmid (m2)

sc-424540-NIC-2mGene KnockoutPuromycin0
(0)

IL-27R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-27Rα CRISPR Activation Plasmid (h)

sc-405846-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα CRISPR Activation Plasmid (h2)

sc-405846-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα Lentiviral Activation Particles (h)

sc-405846-LAChGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα Lentiviral Activation Particles (h2)

sc-405846-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα CRISPR Activation Plasmid (m)

sc-424540-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα CRISPR Activation Plasmid (m2)

sc-424540-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα Lentiviral Activation Particles (m)

sc-424540-LACmGene ActivationPuro, Blast, Hygro0
(0)

IL-27Rα Lentiviral Activation Particles (m2)

sc-424540-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IL-27R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-27Rα siRNA (h)

sc-60836hGene SilencingN/A0
(0)

IL-27Rα shRNA Plasmid (h)

sc-60836-SHhGene SilencingPuromycin0
(0)

IL-27Rα shRNA (h) Lentiviral Particles

sc-60836-VhGene SilencingPuromycin0
(0)

IL-27Rα siRNA (m)

sc-60837mGene SilencingN/A
1
(0)

IL-27Rα shRNA Plasmid (m)

sc-60837-SHmGene SilencingPuromycin
1
(0)

IL-27Rα shRNA (m) Lentiviral Particles

sc-60837-VmGene SilencingPuromycin
1
(0)