Date published: 2026-1-9

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IGFBP Inhibitors

Santa Cruz Biotechnology now offers a broad range of IGFBP Inhibitors for use in various applications. IGFBP Inhibitors are crucial tools for studying the function and regulation of insulin-like growth factor binding proteins (IGFBPs), which play a significant role in modulating the activity and availability of insulin-like growth factors (IGFs). These proteins are involved in numerous cellular processes, including growth, differentiation, and survival. In scientific research, IGFBP Inhibitors are used to explore the downstream effects of inhibiting IGFBPs on IGF-mediated signaling pathways such as PI3K/AKT and MAPK/ERK, which are essential for cell proliferation, metabolism, and survival. Researchers employ IGFBP Inhibitors to study the molecular interactions between IGFBPs and IGFs, as well as to identify potential regulatory pathways and targets for further investigation. Additionally, these inhibitors are valuable in high-throughput screening assays aimed at discovering new modulators of IGFBP activity. The use of IGFBP Inhibitors supports the development of experimental models to dissect the complex signaling networks involving IGFBPs and IGFs, enhancing our understanding of cellular regulation and adaptation. By enabling precise control over IGFBP activity, these inhibitors facilitate comprehensive studies of their role in cellular physiology and broader implications in various biological contexts. View detailed information on our available IGFBP Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

NBI-31772

374620-70-9sc-222047A
sc-222047
sc-222047B
sc-222047C
1 mg
5 mg
10 mg
25 mg
$40.00
$165.00
$272.00
$584.00
(0)

NBI-31772 functions as an insulin-like growth factor binding protein (IGFBP), exhibiting a distinctive affinity for IGF molecules that stabilizes their availability in the extracellular environment. This compound engages in specific non-covalent interactions, such as hydrogen bonding and hydrophobic contacts, which enhance its binding specificity. Its unique conformational flexibility allows for dynamic adjustments in binding, influencing IGF signaling pathways and cellular responses. The compound's interaction kinetics suggest a rapid association phase, followed by a slower dissociation, contributing to its regulatory role in IGF bioactivity.