FRD1 inhibitors belong to a specific chemical class that targets the IFRD1 protein, also known as Interferon-Related Developmental Regulator 1. IFRD1 is a multifunctional protein involved in various cellular processes, including cell cycle regulation, immune response modulation, and cellular differentiation. The chemical class of IFRD1 inhibitors is characterized by molecules that possess the capability to bind selectively to the IFRD1 protein, thereby modulating its activity. This modulation may lead to downstream effects on cellular functions associated with IFRD1, offering potential insights into the intricate regulatory mechanisms governing cellular homeostasis.
IFRD1 inhibitors exhibit diverse molecular architectures, often comprising small organic compounds with specific functional groups that facilitate binding to the target protein. The design and development of IFRD1 inhibitors involve a meticulous understanding of the protein's structure-activity relationship, aiming to enhance binding affinity and specificity. Researchers employ various computational and experimental techniques to identify and optimize compounds within this chemical class, seeking to elucidate the molecular interactions between the inhibitors and the IFRD1 protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate several signaling pathways, potentially reducing the expression of IFRD1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can influence sirtuin activity, which may indirectly affect IFRD1 functions due to cellular stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin can inhibit kinase activity, which could alter IFRD1-related signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an MEK inhibitor; by blocking this pathway, IFRD1 activity could be indirectly reduced. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits PI3K, potentially affecting IFRD1 through downstream signaling changes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, rapamycin may indirectly affect IFRD1 activity via the mTOR signaling pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 inhibits p38 MAPK, possibly impacting IFRD1 by altering stress response pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, which may change IFRD1 activity by affecting related pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin, another PI3K inhibitor, might influence IFRD1 regulatory functions indirectly. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin is known to affect various kinases, potentially modifying IFRD1 activity. | ||||||