IFI-202 Activators

IFI-202 Activators encompass a range of chemical compounds that indirectly augment the protein's functional activity in immune response and inflammation regulation. Resveratrol, by activating SIRT1, influences the NF-κB pathway, enhancing IFI-202's role in immune and inflammatory responses. Similarly, Curcumin and (-)-Epigallocatechin Gallate, by inhibiting the NF-κB pathway, boost IFI-202's function in immune regulation. The flavonoid Quercetin modulates the PI3K/Akt pathway, a crucial player in cell survival and immune responses, thereby indirectly enhancing IFI-202's activity. DL-Sulforaphane activates Nrf2, leading to an improved immune response where IFI-202 is functionally significant. Aspirin, through its anti-inflammatory action, inhibits the COX pathway and modulates NF-κB, indirectly boosting IFI-202's activity in regulating immune responses and inflammation. This modulation is also echoed in the action of Indomethacin.

In addition to these compounds, Omega-3 fatty acids like Eicosapentaenoic Acid modulate inflammatory responses, enhancing IFI-202's role in immune and inflammatory processes. Cholecalciferol and Zinc, each influencing the NF-κB pathway, play crucial roles in enhancing IFI-202's activity in immune response regulation. Spermidine, known for activating autophagy and modulating inflammation, supports IFI-202's function in immune regulation. Lastly, Lithium, by influencing GSK-3 and Wnt signaling pathways, indirectly boosts IFI-202's role in neuroprotective and developmental processes. Collectively, these compounds, through their targeted effects on various signaling pathways, facilitate the enhancement of IFI-202 mediated functions, underscoring their importance in regulating immune and inflammatory responses.