I-FABP Inhibitors
The chemical class termed I-FABP Inhibitors encompasses a specialized group of compounds intricately designed to modulate the activity of Intestinal Fatty Acid-Binding Protein (I-FABP). This protein serves as a pivotal player in the intracellular transport of fatty acids within intestinal epithelial cells. The inhibitors within this class are meticulously crafted to interact with I-FABP in a manner that disrupts its binding capacity and subsequent intracellular fatty acid transport.The development of I-FABP inhibitors involves a keen understanding of the structural nuances of the protein and its binding sites. These inhibitors are meticulously tailored to engage with I-FABP, possibly through specific binding pockets or interaction sites. By doing so, they aim to inhibit the protein's capacity to effectively transport fatty acids, potentially impacting lipid metabolism within intestinal cells. The potency and specificity of these inhibitors are key considerations, with the goal of selectively targeting I-FABP without interfering with other cellular processes.
In the realm of molecular investigation, I-FABP inhibitors assume a role of significance as tools for deciphering the intricate intricacies of fatty acid transport within cells. They stand as key agents, offering insights into the role of I-FABP in cellular lipid dynamics. The pursuit of I-FABP inhibitors underscores a broader ambition to comprehend the molecular orchestration of cellular lipid handling, with each compound forming a thread in the intricate tapestry of cellular metabolism.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
1,1-Dimethylbiguanide, Hydrochloride may indirectly affect FABP2 expression by improving insulin sensitivity and altering lipid metabolism pathways in intestinal cells. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
As a PPARα agonist, fenofibrate could modulate lipid metabolism, potentially leading to changes in FABP2 expression in response to altered fatty acid homeostasis. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is known to modulate lipid metabolism and could influence FABP2 expression through its effects on intestinal lipid handling and insulin sensitivity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may modulate FABP2 expression by affecting inflammatory pathways and insulin signaling, which are involved in the regulation of lipid metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol might influence FABP2 expression through its antioxidant properties and effects on lipid metabolism and insulin sensitivity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
As a PPARγ agonist, pioglitazone could affect the expression of genes involved in fatty acid transport and metabolism, potentially including FABP2. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid might alter FABP2 expression by modulating gene expression through retinoic acid receptors, which are involved in cell growth and differentiation. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Silymarin could influence FABP2 expression through its hepatoprotective and antioxidant effects, potentially affecting lipid metabolism in the liver and intestine. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea extract, may modulate lipid metabolism and inflammation, potentially influencing FABP2 expression. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid, an antioxidant, might affect FABP2 expression through its effects on mitochondrial function and insulin signaling pathways. | ||||||