HoxA7 Activators
HoxA7, being a member of the Hox gene family, is primarily associated with transcriptional regulation during embryonic development. Transcription factors, including those related to the Hox genes, are essential for the orchestration of precise gene expression patterns that guide cellular differentiation and tissue development. In this context, an activator typically refers to a molecule or compound that enhances the expression of a specific gene or set of genes.
HoxA7 activators could be chemical compounds designed to modulate the expression or activity of the HoxA7 gene. These activators might function by interacting with regulatory elements or proteins involved in the transcriptional machinery, thereby promoting the upregulation of HoxA7 expression. Understanding the molecular mechanisms that govern Hox gene regulation, including potential activators, could offer insights into the intricate processes of embryonic development. Researchers might explore these compounds to manipulate gene expression for experimental purposes, shedding light on the broader regulatory networks governing developmental pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can indirectly stimulate HoxA7 gene expression through the activation of the retinoic acid signaling pathway, a critical player in body axis patterning during development. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is involved in DNA methylation processes and could potentially drive HoxA7 gene expression indirectly through epigenetic modifications. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
By inhibiting BMP signaling, Dorsomorphin may facilitate an environment conducive to HoxA7 expression. | ||||||
Purmorphamine | 483367-10-8 | sc-202785 sc-202785A | 1 mg 5 mg | $56.00 $180.00 | 18 | |
Purmorphamine activates the Hedgehog signaling pathway, which interacts with Hox genes, potentially driving HoxA7 expression indirectly. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO can have broad effects on cellular processes and gene expression, potentially including indirect stimulation of HoxA7 expression, though the exact mechanisms are not well-defined. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Cobalt Chloride is used to mimic hypoxia in laboratory settings, which can lead to changes in gene expression, potentially indirectly stimulating HoxA7. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine inhibits DNA methylation, an epigenetic modification that can change gene expression. This could potentially lead to indirect stimulation of HoxA7 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor and can alter gene expression through changes in chromatin structure, potentially indirectly stimulating HoxA7 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone can stimulate gene expression through glucocorticoid receptor signaling. This may indirectly stimulate HoxA7 expression, though the specific mechanisms are not well-defined. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen, an antiestrogen, can stimulate gene expression in certain contexts through estrogen receptor signaling, potentially indirectly stimulating HoxA7 expression. | ||||||