hnRNP E1 Activators
hnRNP E1 Activators are a class of chemical compounds that are associated with the modulation or enhancement of the biological activity of heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1), also known as PCBP1 (Poly(rC)-binding protein 1). hnRNP E1 is a versatile RNA-binding protein found in the nucleus and cytoplasm of eukaryotic cells. This protein is involved in various aspects of RNA metabolism and regulation, making it a pivotal player in gene expression and cellular processes. hnRNP E1 has several functions, including RNA stabilization, splicing regulation, and translational control. It binds to specific RNA sequences, often containing poly(rC) motifs, and interacts with other proteins to form ribonucleoprotein complexes.
hnRNP E1 Activators are believed to interact with hnRNP E1, influencing its RNA-binding affinity, localization, or interactions with other cellular components. By targeting hnRNP E1, these activators can modulate its role in various RNA-related processes, including the regulation of mRNA stability, alternative splicing, and translation. The precise mechanisms by which these activators affect hnRNP E1 function are areas of active research, but their effects have implications for the post-transcriptional control of gene expression. hnRNP E1 has been associated with numerous cellular functions, including mRNA stability, mRNA transport, and translational control. It plays a critical role in diverse physiological processes such as cellular growth, differentiation, and responses to environmental stimuli. Understanding how hnRNP E1 Activators influence hnRNP E1's function is essential for unraveling the complexities of RNA biology and gene regulation within cells.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of Vitamin A, is known to regulate gene expression through retinoic acid receptors and may influence hnRNP E1 expression as part of its broad regulatory effects on cellular differentiation and development. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium butyrate, a short-chain fatty acid, acts as a histone deacetylase inhibitor. It can alter chromatin structure and thereby potentially increase the transcription of various genes, including hnRNP E1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate, a polyphenol from green tea, is known for its antioxidant properties and may modulate gene expression, possibly affecting hnRNP E1 levels through pathways involved in oxidative stress response. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a compound in turmeric, is known to modulate numerous molecular targets and signaling pathways. It may influence hnRNP E1 expression through its effects on transcription factors and gene regulation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol found in grapes, is known to influence gene expression and protein function. Its potential effect on hnRNP E1 expression could be through pathways related to cellular stress and aging. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane, found in cruciferous vegetables, is a compound that activates various cellular pathways. It may induce hnRNP E1 expression through its role in detoxification and antioxidant defense mechanisms. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine, a central nervous system stimulant, may affect gene expression related to energy metabolism and stress response, potentially influencing hnRNP E1 levels. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can impact multiple signaling pathways and gene expression patterns, potentially affecting hnRNP E1 expression as part of its broad biological effects. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin, found in the Coleus forskohlii plant, activates adenylate cyclase and raises cAMP levels, potentially influencing the expression of genes including hnRNP E1 through cAMP-dependent pathways. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen can modulate gene expression through its action on estrogen receptors, potentially impacting hnRNP E1 expression as part of its wider effects. | ||||||