Date published: 2026-1-9

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HES1 Antibodies

Santa Cruz Biotechnology provides a broad selection of HES1 monoclonal antibodies for research focused on understanding HES1 protein functions. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HES1 is a basic helix-loop-helix transcription factor essential for regulating cell fate decisions during development and maintaining stem cell properties. As a key component in the Notch signaling pathway, HES1 influences various biological processes, including differentiation, proliferation, and apoptosis. Research has shown that HES1 alterations are linked to multiple diseases, particularly cancer development and progression. Understanding HES1's molecular mechanisms and cellular functions continues to be an active area of investigation in developmental biology and cancer research. Scientists can explore HES1's role in normal development and disease states through detailed molecular and cellular analyses. Investigating HES1 expression patterns and interactions provides valuable insights into developmental processes and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of HES1's impact on cellular regulation and disease mechanisms.

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HES1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HES1 Antibody (E-5)

sc-166410mouse IgG2b κ237-261 (h)WB, IP, IF, IHC(P), ELISAm, r, h
54
(19)

HES1 Antibody (A-12)

sc-166378mouse IgG1 κ163-194 (h)WB, IP, IF, ELISAm, r, h
12
(4)

HES1 Antibody (F-10)

sc-165996mouse IgG2b κ163-194 (h)WB, IP, IF, ELISAm, r, h
3
(1)

HES1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HES1 CRISPR/Cas9 KO Plasmid (h)

sc-400387hGene KnockoutGFP0
(0)

HES1 HDR Plasmid (h)

sc-400387-HDRhHomology Directed RepairPuromycin0
(0)

HES1 Double Nickase Plasmid (h)

sc-400387-NIChGene KnockoutPuromycin0
(0)

HES1 Double Nickase Plasmid (h2)

sc-400387-NIC-2hGene KnockoutPuromycin0
(0)

HES1 CRISPR/Cas9 KO Plasmid (m)

sc-420832mGene KnockoutGFP0
(0)

HES1 HDR Plasmid (m)

sc-420832-HDRmHomology Directed RepairPuromycin0
(0)

HES1 Double Nickase Plasmid (m)

sc-420832-NICmGene KnockoutPuromycin0
(0)

HES1 Double Nickase Plasmid (m2)

sc-420832-NIC-2mGene KnockoutPuromycin0
(0)

HES1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HES1 CRISPR Activation Plasmid (h)

sc-400387-ACThGene ActivationPuro, Blast, Hygro0
(0)

HES1 CRISPR Activation Plasmid (h2)

sc-400387-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HES1 Lentiviral Activation Particles (h)

sc-400387-LAChGene ActivationPuro, Blast, Hygro0
(0)

HES1 Lentiviral Activation Particles (h2)

sc-400387-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

HES1 CRISPR Activation Plasmid (m)

sc-420832-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HES1 CRISPR Activation Plasmid (m2)

sc-420832-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HES1 Lentiviral Activation Particles (m)

sc-420832-LACmGene ActivationPuro, Blast, Hygro0
(0)

HES1 Lentiviral Activation Particles (m2)

sc-420832-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HES1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HES1 siRNA (h)

sc-37938hGene SilencingN/A
4
(1)

HES1 shRNA Plasmid (h)

sc-37938-SHhGene SilencingPuromycin
4
(1)

HES1 shRNA (h) Lentiviral Particles

sc-37938-VhGene SilencingPuromycin
4
(1)

HES1 siRNA (m)

sc-37939mGene SilencingN/A
3
(0)

HES1 shRNA Plasmid (m)

sc-37939-SHmGene SilencingPuromycin
3
(0)

HES1 shRNA (m) Lentiviral Particles

sc-37939-VmGene SilencingPuromycin
3
(0)

HES1 siRNA (r)

sc-270146rGene SilencingN/A
4
(0)

HES1 shRNA Plasmid (r)

sc-270146-SHrGene SilencingPuromycin
4
(0)

HES1 shRNA (r) Lentiviral Particles

sc-270146-VrGene SilencingPuromycin
4
(0)