Date published: 2025-12-6

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Helios Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Helios Antibodies for advanced research in immunology and cell biology. Helios Antibodies are compatible with multiple experimental techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Helios, also known as IKZF2, is a critical transcription factor involved in the regulation of T cell development and function. It plays a significant role in maintaining immune homeostasis and is essential for the differentiation of regulatory T cells. Understanding Helios function is vital for elucidating mechanisms of immune response and potential therapeutic targets in autoimmune diseases and cancer. Helios Antibodies targeting Helios enable precise detection and characterization of protein expression patterns in various cellular environments. Researchers can effectively track Helios activity across different developmental stages and disease conditions. Advanced imaging techniques combined with Helios monoclonal antibodies allow for detailed visualization of protein localization and interactions. Santa Cruz Biotechnology monoclonal antibodies targeting Helios support researchers worldwide in advancing our understanding of immune system regulation and development of targeted therapies.

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Helios Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Helios Antibody (E-7)

sc-390357mouse IgG1 κ222-280 (h)WB, IP, IF, ELISAm, r, h
5
(2)

Helios Antibody (H-1)

sc-390358mouse IgG2a κ222-280 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Helios CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Helios CRISPR/Cas9 KO Plasmid (h)

sc-402984hGene KnockoutGFP0
(0)

Helios HDR Plasmid (h)

sc-402984-HDRhHomology Directed RepairPuromycin0
(0)

Helios Double Nickase Plasmid (h)

sc-402984-NIChGene KnockoutPuromycin0
(0)

Helios Double Nickase Plasmid (h2)

sc-402984-NIC-2hGene KnockoutPuromycin0
(0)

Helios CRISPR/Cas9 KO Plasmid (m)

sc-423821mGene KnockoutGFP0
(0)

Helios HDR Plasmid (m)

sc-423821-HDRmHomology Directed RepairPuromycin0
(0)

Helios Double Nickase Plasmid (m)

sc-423821-NICmGene KnockoutPuromycin0
(0)

Helios Double Nickase Plasmid (m2)

sc-423821-NIC-2mGene KnockoutPuromycin0
(0)

Helios CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Helios CRISPR Activation Plasmid (h)

sc-402984-ACThGene ActivationPuro, Blast, Hygro0
(0)

Helios CRISPR Activation Plasmid (h2)

sc-402984-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Helios Lentiviral Activation Particles (h)

sc-402984-LAChGene ActivationPuro, Blast, Hygro0
(0)

Helios Lentiviral Activation Particles (h2)

sc-402984-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Helios CRISPR Activation Plasmid (m)

sc-423821-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Helios CRISPR Activation Plasmid (m2)

sc-423821-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Helios Lentiviral Activation Particles (m)

sc-423821-LACmGene ActivationPuro, Blast, Hygro0
(0)

Helios Lentiviral Activation Particles (m2)

sc-423821-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Helios siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Helios siRNA (h)

sc-38007hGene SilencingN/A
1
(0)

Helios shRNA Plasmid (h)

sc-38007-SHhGene SilencingPuromycin
1
(0)

Helios shRNA (h) Lentiviral Particles

sc-38007-VhGene SilencingPuromycin
1
(0)

Helios siRNA (m)

sc-38008mGene SilencingN/A0
(0)

Helios shRNA Plasmid (m)

sc-38008-SHmGene SilencingPuromycin0
(0)

Helios shRNA (m) Lentiviral Particles

sc-38008-VmGene SilencingPuromycin0
(0)