HCF1 Inhibitors

HCF1 inhibitors are compounds that can reduce the activity of the HCF1 protein, either directly or indirectly. These inhibitors often work by targeting specific cellular pathways or processes that are also involved in the function of HCF1.

Some inhibitors, like PD98059 and U0126, function by targeting kinases that are involved in the ERK pathway, which is key for cell proliferation and differentiation. By inhibiting this pathway, these compounds might reduce the activity of HCF1, which is also involved in these cellular processes. Other inhibitors, such as LY294002 and Wortmannin, target PI3K, a kinase that is crucial for cell proliferation and survival. These inhibitors might reduce HCF1 activity, given that HCF1 is also involved in these cellular processes.